TRH | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	4 studies	65% ± 11%	Explore
Mueller cell	4 studies	42% ± 21%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TRH at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	88%	420.32	2335 / 2642	69%	17.37	489 / 705
ovary	94%	302.08	169 / 180	13%	0.49	56 / 430
breast	36%	171.71	164 / 459	39%	54.99	440 / 1118
uterus	49%	215.24	84 / 170	10%	1.14	46 / 459
lung	56%	23.00	325 / 578	3%	0.29	32 / 1155
adrenal gland	10%	2.80	26 / 258	20%	5.93	47 / 230
spleen	26%	7.95	62 / 241	0%	0	0 / 0
prostate	22%	11.01	53 / 245	1%	0.04	4 / 502
heart	22%	19.12	190 / 861	0%	0	0 / 0
peripheral blood	20%	7.61	187 / 929	0%	0	0 / 0
kidney	18%	6.53	16 / 89	1%	0.02	9 / 901
adipose	18%	6.31	214 / 1204	0%	0	0 / 0
skin	16%	4.70	291 / 1809	1%	0.02	7 / 472
eye	0%	0	0 / 0	14%	4.47	11 / 80
blood vessel	10%	2.03	133 / 1335	0%	0	0 / 0
thymus	8%	1.44	50 / 653	0%	0.07	3 / 605
bladder	5%	3.67	1 / 21	1%	5.82	4 / 504
liver	3%	0.84	7 / 226	2%	0.11	7 / 406
esophagus	2%	0.46	32 / 1445	2%	0.03	4 / 183
stomach	2%	0.28	6 / 359	2%	0.03	5 / 286
intestine	1%	0.41	14 / 966	1%	0.04	5 / 527
muscle	1%	0.25	10 / 803	0%	0	0 / 0
pancreas	0%	0.04	1 / 328	0%	0	0 / 178
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0007628	Biological process	adult walking behavior
GO_0014054	Biological process	positive regulation of gamma-aminobutyric acid secretion
GO_0001692	Biological process	histamine metabolic process
GO_0014050	Biological process	negative regulation of glutamate secretion
GO_0042755	Biological process	eating behavior
GO_0032024	Biological process	positive regulation of insulin secretion
GO_0007267	Biological process	cell-cell signaling
GO_0009755	Biological process	hormone-mediated signaling pathway
GO_0030141	Cellular component	secretory granule
GO_0005576	Cellular component	extracellular region
GO_0005515	Molecular function	protein binding
GO_0008437	Molecular function	thyrotropin-releasing hormone activity

Gene name	TRH
Protein name	Pro-thyrotropin-releasing hormone Pro-thyrotropin-releasing hormone (Pro-TRH) (Prothyroliberin) [Cleaved into: Thyrotropin-releasing hormone (TRH) (Protirelin) (TSH-releasing factor) (Thyroliberin) (Thyrotropin-releasing factor) (TRF)]
Synonyms
Description	FUNCTION: As a component of the hypothalamic-pituitary-thyroid axis, it controls the secretion of thyroid-stimulating hormone (TSH) and is involved in thyroid hormone synthesis regulation. It also operates as modulator of hair growth. It promotes hair-shaft elongation, prolongs the hair cycle growth phase (anagen) and antagonizes its termination (catagen) by TGFB2. It stimulates proliferation and inhibits apoptosis of hair matrix keratinocytes. . FUNCTION: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. .
Accessions	P20396 ENST00000507066.1 ENST00000302649.4 D6RFM1

TRH report