TREX2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TREX2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TREX2 at tissue level.

III. Associated gene sets

GO_0006308Biological processDNA catabolic process
GO_0006281Biological processDNA repair
GO_0006259Biological processDNA metabolic process
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0008296Molecular function3'-5'-DNA exonuclease activity
GO_0003677Molecular functionDNA binding
GO_0042803Molecular functionprotein homodimerization activity
GO_0008311Molecular functiondouble-stranded DNA 3'-5' DNA exonuclease activity
GO_0005515Molecular functionprotein binding
GO_0060090Molecular functionmolecular adaptor activity
GO_0000287Molecular functionmagnesium ion binding

IV. Literature review

[source]
Gene nameTREX2
Protein nameThree prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2)
Synonyms
DescriptionFUNCTION: Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair. .

AccessionsENST00000338525.7 [Q9BQ50-2]
ENST00000393862.7 [Q9BQ50-2]
ENST00000370231.3 [Q9BQ50-2]
ENST00000370232.4 [Q9BQ50-1]
ENST00000330912.7 [Q9BQ50-2]
ENST00000370212.5 [Q9BQ50-1]
ENST00000334497.7 [Q9BQ50-1]
Q9BQ50