Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 9 studies | 23% ± 6% | |
epithelial cell | 7 studies | 37% ± 13% | |
ciliated cell | 7 studies | 24% ± 8% | |
glutamatergic neuron | 6 studies | 40% ± 23% | |
GABAergic neuron | 6 studies | 34% ± 21% | |
basal cell | 5 studies | 28% ± 13% | |
astrocyte | 5 studies | 24% ± 5% | |
neuron | 4 studies | 26% ± 8% | |
interneuron | 4 studies | 35% ± 20% | |
microglial cell | 3 studies | 16% ± 1% | |
smooth muscle cell | 3 studies | 17% ± 1% | |
retina horizontal cell | 3 studies | 24% ± 6% | |
erythroblast | 3 studies | 32% ± 9% | |
abnormal cell | 3 studies | 30% ± 10% | |
macrophage | 3 studies | 17% ± 2% | |
fibroblast | 3 studies | 22% ± 5% | |
dendritic cell | 3 studies | 26% ± 5% | |
erythrocyte | 3 studies | 33% ± 12% | |
oligodendrocyte | 3 studies | 21% ± 3% | |
oligodendrocyte precursor cell | 3 studies | 23% ± 6% | |
CD4-positive, alpha-beta T cell | 3 studies | 29% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3090.66 | 1445 / 1445 | 100% | 34.21 | 183 / 183 |
ovary | 100% | 3837.80 | 180 / 180 | 100% | 41.21 | 430 / 430 |
stomach | 100% | 2500.50 | 359 / 359 | 100% | 52.09 | 286 / 286 |
skin | 100% | 4078.56 | 1809 / 1809 | 100% | 40.46 | 470 / 472 |
lung | 100% | 2318.63 | 577 / 578 | 100% | 32.89 | 1152 / 1155 |
intestine | 100% | 2700.77 | 964 / 966 | 99% | 59.51 | 524 / 527 |
breast | 100% | 3287.64 | 459 / 459 | 99% | 37.25 | 1106 / 1118 |
pancreas | 100% | 2814.46 | 328 / 328 | 99% | 25.88 | 176 / 178 |
prostate | 100% | 2781.54 | 245 / 245 | 99% | 31.17 | 496 / 502 |
brain | 98% | 2424.99 | 2600 / 2642 | 100% | 35.60 | 704 / 705 |
kidney | 100% | 3060.67 | 89 / 89 | 98% | 35.98 | 885 / 901 |
uterus | 100% | 3538.88 | 170 / 170 | 97% | 33.71 | 447 / 459 |
bladder | 100% | 3146.76 | 21 / 21 | 97% | 37.86 | 488 / 504 |
liver | 100% | 3499.52 | 226 / 226 | 97% | 32.59 | 392 / 406 |
thymus | 100% | 2342.21 | 652 / 653 | 97% | 19.68 | 585 / 605 |
adrenal gland | 100% | 2945.41 | 258 / 258 | 90% | 21.18 | 207 / 230 |
adipose | 100% | 2917.72 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 35.31 | 29 / 29 |
muscle | 100% | 5786.95 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2539.62 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 35.49 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.81 | 1 / 1 |
blood vessel | 100% | 2618.40 | 1333 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 99% | 49.81 | 79 / 80 |
heart | 95% | 2790.76 | 818 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 65% | 2363.88 | 600 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1901856 | Biological process | negative regulation of cellular respiration |
GO_0061077 | Biological process | chaperone-mediated protein folding |
GO_1903427 | Biological process | negative regulation of reactive oxygen species biosynthetic process |
GO_0009386 | Biological process | translational attenuation |
GO_1903751 | Biological process | negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide |
GO_0006457 | Biological process | protein folding |
GO_0016020 | Cellular component | membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005758 | Cellular component | mitochondrial intermembrane space |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0071944 | Cellular component | cell periphery |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0019901 | Molecular function | protein kinase binding |
GO_0051082 | Molecular function | unfolded protein binding |
GO_0140662 | Molecular function | ATP-dependent protein folding chaperone |
GO_0005524 | Molecular function | ATP binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005164 | Molecular function | tumor necrosis factor receptor binding |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | TRAP1 |
Protein name | TNF receptor associated protein 1 Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) TNF receptor associated protein 1 (TNF receptor-associated protein 1, isoform CRA_b) TNF receptor-associated protein 1 TRAP1 protein TNF receptor-associated protein 1 (cDNA FLJ33058 fis, clone TRACH1000181, highly similar to Heat shock protein 75 kDa, mitochondrial) |
Synonyms | hCG_16634 HSP75 |
Description | FUNCTION: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. . |
Accessions | I3L2D5 ENST00000575707.5 I3L239 I3L253 I3L3L4 I3L0P6 Q5CAQ4 Q12931 ENST00000574175.1 ENST00000571538.5 Q9BV61 I3L4L7 ENST00000538171.5 [Q12931-2] ENST00000246957.10 [Q12931-1] ENST00000570403.1 ENST00000575671.5 I3L0K7 K0A7K7 ENST00000571804.5 ENST00000576335.5 ENST00000571011.1 |