TPRX1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TPRX1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TPRX1 at tissue level.

III. Associated gene sets

GO_0160021Biological processmaternal-to-zygotic transition of gene expression
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameTPRX1
Protein nameTetra-peptide repeat homeobox protein 1
CRX like homeobox 2 (Tetrapeptide repeat homeobox 1)
Tetrapeptide repeat homeobox 1
TPRX1 protein
Synonyms
DescriptionFUNCTION: Transcription factor expressed after fertilization required for zygotic genome activation (ZGA), a critical event in early embryonic development during which the developmental control passes from maternally provided mRNAs to the expression of the zygotic genome after fertilization . Binds and activates expression of key ZGA marker genes, such as NANOGNB, ZSCAN4, DUXB, KLF5 and DPPA3 . Binds to regulatory DNA sequences containing a 5'-TAATCC-3' sequence motif . .

AccessionsENST00000322175.8
D2CFI5
ENST00000698655.1
B7ZMM8
A0A8V8TMK4
Q8N7U7
A0A8V8TM49
ENST00000535759.2