TNP2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TNP2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TNP2 at tissue level.

III. Associated gene sets

GO_0035092Biological processsperm DNA condensation
GO_0007283Biological processspermatogenesis
GO_0010954Biological processpositive regulation of protein processing
GO_0007340Biological processacrosome reaction
GO_0007341Biological processpenetration of zona pellucida
GO_0005730Cellular componentnucleolus
GO_0000786Cellular componentnucleosome
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameTNP2
Protein nameNuclear transition protein 2
Nuclear transition protein 2 (TP-2) (TP2)
SynonymshCG_15065
DescriptionFUNCTION: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. .

FUNCTION: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. .

FUNCTION: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. .

FUNCTION: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. .

AccessionsQ4VB56
ENST00000312693.4
A0A2R8Y7P0
ENST00000560751.1
Q4VB54
Q05952