TNFRSF8 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TNFRSF8 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0032759Biological processpositive regulation of TRAIL production
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0071260Biological processcellular response to mechanical stimulus
GO_0043065Biological processpositive regulation of apoptotic process
GO_0032760Biological processpositive regulation of tumor necrosis factor production
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0002020Molecular functionprotease binding
GO_0004888Molecular functiontransmembrane signaling receptor activity

IV. Literature review

[source]
Gene nameTNFRSF8
Protein nameTNFRSF8 protein
Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
TNF receptor superfamily member 8
SynonymsD1S166E
CD30
DescriptionFUNCTION: Receptor for TNFSF8/CD30L . May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B . .

AccessionsENST00000413146.6 [P28908-2]
D6RAG8
P28908
ENST00000514649.5
A5D8T4
Q6GMU3
ENST00000263932.7 [P28908-1]
ENST00000417814.3 [P28908-3]