Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| basal cell | 12 studies | 39% ± 18% | |
| epithelial cell | 11 studies | 35% ± 19% | |
| ciliated cell | 8 studies | 28% ± 12% | |
| respiratory goblet cell | 7 studies | 46% ± 10% | |
| club cell | 5 studies | 36% ± 15% | |
| secretory cell | 5 studies | 47% ± 11% | |
| goblet cell | 5 studies | 29% ± 12% | |
| squamous epithelial cell | 4 studies | 53% ± 17% | |
| hillock cell | 3 studies | 35% ± 15% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 3 studies | 45% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 95% | 3782.81 | 20 / 21 | 78% | 68.52 | 391 / 504 |
| stomach | 69% | 608.82 | 246 / 359 | 92% | 59.18 | 262 / 286 |
| intestine | 62% | 3357.81 | 599 / 966 | 96% | 73.76 | 504 / 527 |
| esophagus | 43% | 4703.70 | 619 / 1445 | 87% | 52.02 | 160 / 183 |
| lung | 40% | 186.65 | 234 / 578 | 81% | 62.60 | 940 / 1155 |
| kidney | 100% | 3117.54 | 89 / 89 | 3% | 1.59 | 25 / 901 |
| ureter | 0% | 0 | 0 / 0 | 100% | 49.96 | 1 / 1 |
| pancreas | 5% | 9.02 | 15 / 328 | 88% | 83.56 | 156 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 60.30 | 40 / 45 |
| uterus | 11% | 87.10 | 19 / 170 | 71% | 53.33 | 325 / 459 |
| ovary | 2% | 2.73 | 3 / 180 | 66% | 26.04 | 283 / 430 |
| prostate | 63% | 1070.18 | 154 / 245 | 2% | 0.38 | 9 / 502 |
| skin | 58% | 312.13 | 1044 / 1809 | 1% | 0.27 | 7 / 472 |
| thymus | 7% | 13.66 | 43 / 653 | 49% | 20.92 | 299 / 605 |
| breast | 0% | 21.22 | 2 / 459 | 8% | 2.28 | 84 / 1118 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.92 | 5 / 406 |
| brain | 1% | 1.78 | 30 / 2642 | 0% | 0 | 0 / 705 |
| adrenal gland | 1% | 0.73 | 2 / 258 | 0% | 0 | 0 / 230 |
| adipose | 1% | 3.26 | 9 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 1.10 | 8 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 10.26 | 3 / 929 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.50 | 1 / 803 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.18 | 1 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0010468 | Biological process | regulation of gene expression |
| GO_0016485 | Biological process | protein processing |
| GO_0046598 | Biological process | positive regulation of viral entry into host cell |
| GO_0045967 | Biological process | negative regulation of growth rate |
| GO_0009611 | Biological process | response to wounding |
| GO_0006508 | Biological process | proteolysis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0030141 | Cellular component | secretory granule |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0008236 | Molecular function | serine-type peptidase activity |
| GO_0004252 | Molecular function | serine-type endopeptidase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TMPRSS4 |
| Protein name | Transmembrane serine protease 4 Transmembrane protease, serine 4, isoform CRA_c (Transmembrane serine protease 4) Transmembrane protease serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (CAPH2) (Membrane-type serine protease 2) (MT-SP2) [Cleaved into: Transmembrane protease serine 4 catalytic chain] |
| Synonyms | TMPRSS3 hCG_41152 UNQ776/PRO1570 |
| Description | FUNCTION: Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity . Seems to be capable of activating ENaC (By similarity). .; FUNCTION: (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. . |
| Accessions | ENST00000517544.1 ENST00000534111.5 [Q9NRS4-3] A0A087WTU6 ENST00000437212.8 [Q9NRS4-1] ENST00000524218.1 ENST00000517483.5 H0YBM5 G3V124 H0YAX8 ENST00000523251.5 [Q9NRS4-4] E5RJR8 ENST00000522307.5 ENST00000522824.5 [Q9NRS4-2] E7ESG9 ENST00000519236.5 Q9NRS4 ENST00000616579.4 ENST00000522151.5 E5RIH1 |
