I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 38% ± 12% | |
| GABAergic neuron | 3 studies | 37% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 38% ± 12% | |
| GABAergic neuron | 3 studies | 37% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 30% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 91% | 121.67 | 223 / 245 | 72% | 1.71 | 363 / 502 |
| lung | 99% | 291.10 | 570 / 578 | 52% | 0.89 | 602 / 1155 |
| adrenal gland | 100% | 400.41 | 257 / 258 | 44% | 3.48 | 102 / 230 |
| kidney | 99% | 274.99 | 88 / 89 | 44% | 1.15 | 394 / 901 |
| brain | 94% | 1344.97 | 2495 / 2642 | 45% | 0.91 | 318 / 705 |
| pancreas | 100% | 404.00 | 328 / 328 | 34% | 0.51 | 61 / 178 |
| breast | 85% | 79.50 | 389 / 459 | 29% | 0.48 | 325 / 1118 |
| ovary | 64% | 52.68 | 116 / 180 | 45% | 0.84 | 193 / 430 |
| skin | 78% | 160.14 | 1409 / 1809 | 23% | 0.60 | 107 / 472 |
| muscle | 99% | 433.01 | 791 / 803 | 0% | 0 | 0 / 0 |
| spleen | 98% | 164.26 | 236 / 241 | 0% | 0 | 0 / 0 |
| esophagus | 45% | 32.63 | 649 / 1445 | 45% | 0.74 | 83 / 183 |
| stomach | 62% | 68.98 | 224 / 359 | 22% | 0.35 | 64 / 286 |
| uterus | 45% | 30.36 | 77 / 170 | 35% | 0.92 | 160 / 459 |
| bladder | 52% | 35.52 | 11 / 21 | 24% | 0.41 | 120 / 504 |
| thymus | 60% | 44.66 | 392 / 653 | 15% | 0.52 | 92 / 605 |
| adipose | 75% | 74.38 | 905 / 1204 | 0% | 0 | 0 / 0 |
| intestine | 55% | 46.51 | 530 / 966 | 15% | 0.22 | 78 / 527 |
| liver | 30% | 19.27 | 67 / 226 | 23% | 0.52 | 92 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 41% | 0.61 | 12 / 29 |
| eye | 0% | 0 | 0 / 0 | 31% | 0.49 | 25 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 22% | 0.38 | 10 / 45 |
| blood vessel | 20% | 14.33 | 271 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 18% | 22.65 | 165 / 929 | 0% | 0 | 0 / 0 |
| heart | 14% | 9.18 | 120 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0043204 | Cellular component | perikaryon |
| GO_0005829 | Cellular component | cytosol |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0015267 | Molecular function | channel activity |
| GO_0022832 | Molecular function | voltage-gated channel activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | TMEM266 |
| Protein name | Transmembrane protein 266 Transmembrane protein 266 (hTMEM266) (HV1-related protein 1) (HsHVRP1) |
| Synonyms | C15orf27 HVRP1 |
| Description | FUNCTION: Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum . Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear . Undergoes both rapid and slow structural rearrangements in response to changes in voltage . Contains a zinc-binding site that can regulate the slow conformational transition . . |
| Accessions | Q2M3C6 ENST00000484722.5 ENST00000388942.8 [Q2M3C6-1] H3BM28 H0YNC9 ENST00000561302.5 |
