TMEM164 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0160020Biological processpositive regulation of ferroptosis
GO_0016020Cellular componentmembrane

IV. Literature review

[source]
Gene nameTMEM164
Protein nameTransmembrane protein 164
Transmembrane protein 164 (cDNA: FLJ22679 fis, clone HSI10687)
SynonymshCG_20304
RP13-360B22.2
DescriptionFUNCTION: Positive regulator of ferroptosis. Selectively mediates ATG5-dependent autophagosome formation during ferroptosis, rather than during starvation, and regulates the degradation of ferritin, GPX4 and lipid droplets to increase iron accumulation and lipid peroxidation, thereby promoting ferroptotic cell death. .

AccessionsENST00000372073.5 [Q5U3C3-1]
ENST00000372072.7 [Q5U3C3-2]
ENST00000288381.4
Q5U3C3
ENST00000372068.7 [Q5U3C3-1]
A1PI58