TENT5B | OmnibusX

Name	Number of supported studies	Average coverage
type I pneumocyte	3 studies	24% ± 4%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of TENT5B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	99%	9001.80	1431 / 1445	70%	27.45	129 / 183
skin	83%	8536.42	1504 / 1809	86%	29.11	407 / 472
breast	61%	1788.09	282 / 459	89%	28.39	992 / 1118
uterus	60%	1959.95	102 / 170	83%	41.46	381 / 459
prostate	49%	1234.83	119 / 245	75%	10.70	378 / 502
lung	59%	1331.04	339 / 578	64%	10.32	736 / 1155
bladder	76%	3895.62	16 / 21	39%	8.28	197 / 504
ureter	0%	0	0 / 0	100%	4.21	1 / 1
blood vessel	96%	5483.16	1286 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	89%	44.95	40 / 45
intestine	67%	2926.69	644 / 966	19%	3.17	102 / 527
ovary	11%	251.76	19 / 180	66%	8.17	285 / 430
thymus	16%	236.11	105 / 653	59%	6.09	355 / 605
heart	69%	1750.33	593 / 861	0%	0	0 / 0
stomach	38%	1495.13	135 / 359	28%	4.06	80 / 286
pancreas	0%	0	0 / 328	42%	3.71	75 / 178
kidney	15%	160.81	13 / 89	25%	2.90	229 / 901
adipose	29%	490.31	345 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	25%	1.63	20 / 80
brain	0%	1.26	3 / 2642	25%	3.33	175 / 705
adrenal gland	0%	0	0 / 258	12%	1.45	28 / 230
liver	0%	0	0 / 226	3%	0.30	14 / 406
muscle	0%	6.99	4 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0

GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0048255	Biological process	mRNA stabilization
GO_0045786	Biological process	negative regulation of cell cycle
GO_0045727	Biological process	positive regulation of translation
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_1990817	Molecular function	poly(A) RNA polymerase activity
GO_0005515	Molecular function	protein binding

Gene name	TENT5B
Protein name	Terminal nucleotidyltransferase 5B (EC 2.7.7.19) (Non-canonical poly(A) polymerase FAM46B)
Synonyms	FAM46B
Description	FUNCTION: Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group in an ATP hydrolysis-dependent manner . May be involved in maintaining the translation efficiency of at least some genes through preventing degradation of their mRNAs . Prefers RNA molecules that are adenosine-rich close to 3'-end . In addition, may inhibit cell proliferation and cell cycle progression through ubiquitination of beta-catenin/CTNNB1 . .
Accessions	ENST00000289166.6 Q96A09

TENT5B report