TDRD7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0002089Biological processlens morphogenesis in camera-type eye
GO_0007283Biological processspermatogenesis
GO_0030719Biological processP granule organization
GO_0070306Biological processlens fiber cell differentiation
GO_0010608Biological processpost-transcriptional regulation of gene expression
GO_0034587Biological processpiRNA processing
GO_0033391Cellular componentchromatoid body
GO_0035770Cellular componentribonucleoprotein granule
GO_0043186Cellular componentP granule
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0003729Molecular functionmRNA binding

IV. Literature review

[source]
Gene nameTDRD7
Protein nameTudor domain-containing protein 7 (PCTAIRE2-binding protein) (Tudor repeat associator with PCTAIRE-2) (Trap)
SynonymsPCTAIRE2BP
DescriptionFUNCTION: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis. .

AccessionsQ8NHU6
ENST00000355295.5 [Q8NHU6-1]