Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 19 studies | 48% ± 18% | |
| epithelial cell | 5 studies | 27% ± 6% | |
| deuterosomal cell | 4 studies | 21% ± 4% | |
| astrocyte | 4 studies | 34% ± 11% | |
| fibroblast | 3 studies | 22% ± 6% | |
| GABAergic neuron | 3 studies | 23% ± 5% | |
| glutamatergic neuron | 3 studies | 32% ± 10% | |
| ependymal cell | 3 studies | 43% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 1522.36 | 245 / 245 | 100% | 13.74 | 502 / 502 |
| brain | 99% | 886.58 | 2617 / 2642 | 100% | 15.05 | 703 / 705 |
| breast | 100% | 1313.69 | 459 / 459 | 98% | 15.75 | 1099 / 1118 |
| adrenal gland | 100% | 1466.38 | 258 / 258 | 98% | 13.42 | 226 / 230 |
| kidney | 100% | 1629.53 | 89 / 89 | 98% | 20.28 | 884 / 901 |
| thymus | 100% | 2719.58 | 653 / 653 | 98% | 15.98 | 592 / 605 |
| ovary | 100% | 1868.81 | 180 / 180 | 97% | 11.35 | 416 / 430 |
| pancreas | 99% | 650.44 | 326 / 328 | 97% | 9.43 | 172 / 178 |
| skin | 100% | 1062.30 | 1806 / 1809 | 94% | 9.97 | 446 / 472 |
| lung | 100% | 1242.08 | 577 / 578 | 92% | 8.16 | 1066 / 1155 |
| bladder | 100% | 1159.81 | 21 / 21 | 87% | 6.20 | 436 / 504 |
| uterus | 100% | 1571.60 | 170 / 170 | 86% | 7.06 | 394 / 459 |
| intestine | 98% | 1002.61 | 947 / 966 | 84% | 5.21 | 443 / 527 |
| esophagus | 100% | 921.54 | 1441 / 1445 | 75% | 5.08 | 137 / 183 |
| stomach | 97% | 761.36 | 350 / 359 | 76% | 4.57 | 218 / 286 |
| liver | 93% | 400.54 | 211 / 226 | 62% | 4.12 | 253 / 406 |
| adipose | 100% | 1040.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 626.11 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1121.84 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 96% | 8.32 | 77 / 80 |
| heart | 95% | 998.43 | 822 / 861 | 0% | 0 | 0 / 0 |
| muscle | 92% | 606.51 | 740 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 4.91 | 37 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 69% | 6.41 | 20 / 29 |
| peripheral blood | 28% | 171.14 | 258 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008589 | Biological process | regulation of smoothened signaling pathway |
| GO_0060271 | Biological process | cilium assembly |
| GO_0021523 | Biological process | somatic motor neuron differentiation |
| GO_0001841 | Biological process | neural tube formation |
| GO_1904491 | Biological process | protein localization to ciliary transition zone |
| GO_0001701 | Biological process | in utero embryonic development |
| GO_0021904 | Biological process | dorsal/ventral neural tube patterning |
| GO_0021956 | Biological process | central nervous system interneuron axonogenesis |
| GO_0021537 | Biological process | telencephalon development |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0036038 | Cellular component | MKS complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0016020 | Cellular component | membrane |
| Gene name | TCTN1 |
| Protein name | Tectonic family member 1 Tectonic family member 1 (cDNA FLJ55161, highly similar to Tectonic-1) Tectonic-1 TCTN1 protein |
| Synonyms | TECT1 UNQ9369/PRO34160 |
| Description | FUNCTION: Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23 (By similarity). . |
| Accessions | ENST00000681395.1 ENST00000490514.5 ENST00000680512.1 ENST00000680068.1 J3KPW2 E9PIB8 A0A7P0TAW1 ENST00000552318.5 ENST00000679617.1 ENST00000680445.1 F8VQ12 ENST00000680548.1 S4R3G2 A0A7P0T8R0 ENST00000546643.1 ENST00000549123.6 Q8NEI8 S4R2Y1 ENST00000498072.5 ENST00000679713.1 A0A7P0T9A6 A0A087X1J4 ENST00000464809.5 ENST00000480648.5 ENST00000377654.5 ENST00000471804.7 ENST00000681851.1 ENST00000679473.1 E9PR69 F8VSB8 ENST00000614115.5 ENST00000681604.1 Q05BR9 ENST00000397656.8 B4DIB9 ENST00000680203.1 ENST00000547461.3 ENST00000679401.1 ENST00000481720.5 Q2MV58 S4R3M8 E9PNE4 A0A7P0TA68 ENST00000681437.1 ENST00000551590.5 [Q2MV58-1] ENST00000681807.1 A0A0A0MRU7 ENST00000478122.6 S4R339 A0A7P0T8M6 ENST00000495659.6 ENST00000550703.6 ENST00000397659.9 [Q2MV58-2] ENST00000397655.7 [Q2MV58-3] |
