Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 19 studies | 26% ± 8% | |
| vein endothelial cell | 9 studies | 27% ± 11% | |
| capillary endothelial cell | 8 studies | 22% ± 3% | |
| enterocyte | 5 studies | 27% ± 12% | |
| macrophage | 5 studies | 19% ± 2% | |
| epithelial cell of proximal tubule | 4 studies | 22% ± 5% | |
| epithelial cell | 4 studies | 33% ± 17% | |
| endothelial cell of vascular tree | 4 studies | 20% ± 3% | |
| non-classical monocyte | 4 studies | 19% ± 2% | |
| endothelial cell of artery | 4 studies | 18% ± 3% |
Insufficient scRNA-seq data for expression of TCN2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 100% | 7538.03 | 89 / 89 | 97% | 193.42 | 877 / 901 |
| lung | 100% | 3771.22 | 578 / 578 | 93% | 53.73 | 1077 / 1155 |
| thymus | 100% | 2649.47 | 653 / 653 | 91% | 79.67 | 549 / 605 |
| brain | 90% | 954.39 | 2382 / 2642 | 100% | 56.12 | 705 / 705 |
| breast | 100% | 3659.18 | 459 / 459 | 88% | 28.87 | 980 / 1118 |
| uterus | 99% | 2188.82 | 169 / 170 | 82% | 36.83 | 378 / 459 |
| adrenal gland | 100% | 2905.86 | 258 / 258 | 80% | 28.76 | 183 / 230 |
| stomach | 99% | 1342.26 | 357 / 359 | 77% | 22.86 | 220 / 286 |
| intestine | 100% | 2412.77 | 963 / 966 | 76% | 23.86 | 403 / 527 |
| pancreas | 81% | 596.42 | 266 / 328 | 95% | 45.80 | 169 / 178 |
| bladder | 100% | 1623.05 | 21 / 21 | 76% | 28.74 | 381 / 504 |
| ovary | 97% | 1412.73 | 175 / 180 | 78% | 28.84 | 336 / 430 |
| prostate | 99% | 1604.03 | 243 / 245 | 75% | 17.18 | 376 / 502 |
| skin | 77% | 700.16 | 1399 / 1809 | 95% | 74.10 | 449 / 472 |
| esophagus | 82% | 1177.03 | 1179 / 1445 | 58% | 15.24 | 106 / 183 |
| liver | 62% | 477.30 | 140 / 226 | 67% | 20.70 | 271 / 406 |
| adipose | 100% | 3860.55 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 123.58 | 29 / 29 |
| spleen | 100% | 4305.91 | 241 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 41.35 | 79 / 80 |
| heart | 99% | 1420.16 | 850 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 94% | 1662.46 | 1255 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 84% | 1631.15 | 785 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 84% | 31.69 | 38 / 45 |
| muscle | 30% | 171.03 | 243 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0015889 | Biological process | cobalamin transport |
| GO_0006824 | Biological process | cobalt ion transport |
| GO_0005615 | Cellular component | extracellular space |
| GO_0043202 | Cellular component | lysosomal lumen |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031419 | Molecular function | cobalamin binding |
| GO_0140355 | Molecular function | cargo receptor ligand activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | TCN2 |
| Protein name | Transcobalamin-2 (TC-2) (Transcobalamin II) (TC II) (TCII) Transcobalamin-2 (Transcobalamin II) |
| Synonyms | TC2 |
| Description | FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . FUNCTION: Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells. . |
| Accessions | ENST00000407817.3 [P20062-2] A0A8V8TNC5 ENST00000450638.5 ENST00000698266.1 A0A8V8TLJ5 ENST00000698269.1 ENST00000698271.1 A0A8V8TM37 A0A8V8TN28 ENST00000698265.1 A0A8V8TLM2 A0A8V8TM34 A0A8V8TLL7 ENST00000698263.1 ENST00000698273.1 ENST00000698272.1 A0A8V8TNC0 B5MBX2 A0A8V8TLK0 F8WE86 ENST00000698267.1 ENST00000215838.8 [P20062-1] ENST00000698268.1 P20062 ENST00000405742.7 ENST00000698270.1 A0A8V8TN24 |