TBL3 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TBL3 at tissue level.

III. Associated gene sets

GO_0000480Biological processendonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0000472Biological processendonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO_0042274Biological processribosomal small subunit biogenesis
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0030686Cellular component90S preribosome
GO_0032040Cellular componentsmall-subunit processome
GO_0034511Molecular functionU3 snoRNA binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameTBL3
Protein nameTransducin beta-like protein 3 (WD repeat-containing protein SAZD)
Transducin beta like 3
TBL3 protein
SynonymsSAZD
DescriptionFUNCTION: Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome. .

AccessionsQ12788
ENST00000568546.6
A0JLS5
ENST00000709263.1
J3KNP2
H3BN88
ENST00000561907.5
ENST00000332704.5