I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasma cell | 3 studies | 21% ± 1% | |
| GABAergic neuron | 3 studies | 37% ± 4% | |
| glutamatergic neuron | 3 studies | 59% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| plasma cell | 3 studies | 21% ± 1% | |
| GABAergic neuron | 3 studies | 37% ± 4% | |
| glutamatergic neuron | 3 studies | 59% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 32% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 448.61 | 1445 / 1445 | 97% | 11.89 | 178 / 183 |
| intestine | 100% | 505.59 | 963 / 966 | 97% | 7.45 | 510 / 527 |
| stomach | 99% | 313.69 | 356 / 359 | 97% | 7.41 | 276 / 286 |
| ovary | 100% | 897.87 | 180 / 180 | 96% | 7.57 | 411 / 430 |
| skin | 100% | 816.15 | 1809 / 1809 | 93% | 10.82 | 440 / 472 |
| lung | 97% | 289.05 | 560 / 578 | 94% | 8.33 | 1083 / 1155 |
| prostate | 99% | 323.34 | 242 / 245 | 91% | 5.45 | 455 / 502 |
| uterus | 100% | 523.37 | 170 / 170 | 87% | 6.05 | 398 / 459 |
| breast | 100% | 667.21 | 459 / 459 | 86% | 6.94 | 963 / 1118 |
| pancreas | 98% | 310.48 | 321 / 328 | 84% | 4.25 | 150 / 178 |
| thymus | 100% | 413.41 | 653 / 653 | 82% | 3.76 | 495 / 605 |
| kidney | 100% | 364.85 | 89 / 89 | 81% | 4.67 | 728 / 901 |
| adrenal gland | 100% | 527.14 | 258 / 258 | 77% | 3.47 | 177 / 230 |
| bladder | 100% | 469.00 | 21 / 21 | 75% | 5.04 | 380 / 504 |
| brain | 91% | 400.62 | 2397 / 2642 | 64% | 2.27 | 452 / 705 |
| adipose | 100% | 687.18 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 738.43 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 367.72 | 1328 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 446.89 | 794 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 10.78 | 44 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 18.19 | 26 / 29 |
| eye | 0% | 0 | 0 / 0 | 89% | 7.84 | 71 / 80 |
| heart | 76% | 161.71 | 655 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 47% | 575.71 | 435 / 929 | 0% | 0 | 0 / 0 |
| liver | 1% | 1.65 | 3 / 226 | 11% | 0.49 | 43 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0051123 | Biological process | RNA polymerase II preinitiation complex assembly |
| GO_0060261 | Biological process | positive regulation of transcription initiation by RNA polymerase II |
| GO_0042789 | Biological process | mRNA transcription by RNA polymerase II |
| GO_0006367 | Biological process | transcription initiation at RNA polymerase II promoter |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0048477 | Biological process | oogenesis |
| GO_0005669 | Cellular component | transcription factor TFIID complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0005634 | Cellular component | nucleus |
| GO_0051059 | Molecular function | NF-kappaB binding |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0003677 | Molecular function | DNA binding |
| GO_0016251 | Molecular function | RNA polymerase II general transcription initiation factor activity |
| Gene name | TAF4B |
| Protein name | HCG38478, isoform CRA_a (TATA-box binding protein associated factor 4b) Transcription initiation factor TFIID subunit 4B (Transcription initiation factor TFIID 105 kDa subunit) (TAF(II)105) (TAFII-105) (TAFII105) Alternative protein TAF4B |
| Synonyms | hCG_38478 TAFII105 TAF2C2 |
| Description | FUNCTION: Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis. . |
| Accessions | ENST00000269142.10 [Q92750-1] J3KTH2 L0R5D1 Q92750 ENST00000418698.3 [Q92750-2] ENST00000578121.5 |
