TAF1A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TAF1A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TAF1A at tissue level.

III. Associated gene sets

GO_0006366Biological processtranscription by RNA polymerase II
GO_0006360Biological processtranscription by RNA polymerase I
GO_0005668Cellular componentRNA polymerase transcription factor SL1 complex
GO_0005654Cellular componentnucleoplasm
GO_0015630Cellular componentmicrotubule cytoskeleton
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTAF1A
Protein nameTATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A)
TATA-box binding protein associated factor, RNA polymerase I subunit A
Synonyms
DescriptionFUNCTION: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. .

AccessionsQ5JRA7
ENST00000352967.9 [Q15573-1]
ENST00000391883.2
ENST00000350027.8 [Q15573-1]
ENST00000366890.5 [Q15573-2]
Q15573