TAF13 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TAF13 at tissue level.

III. Associated gene sets

GO_0051123Biological processRNA polymerase II preinitiation complex assembly
GO_0006366Biological processtranscription by RNA polymerase II
GO_0060261Biological processpositive regulation of transcription initiation by RNA polymerase II
GO_0006367Biological processtranscription initiation at RNA polymerase II promoter
GO_0006352Biological processDNA-templated transcription initiation
GO_0042789Biological processmRNA transcription by RNA polymerase II
GO_0005730Cellular componentnucleolus
GO_0005669Cellular componenttranscription factor TFIID complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding
GO_0017025Molecular functionTBP-class protein binding
GO_0016251Molecular functionRNA polymerase II general transcription initiation factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTAF13
Protein nameTATA-box binding protein associated factor 13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18)
SynonymsTAFII18
TAF2K
DescriptionFUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription . TFIID recognizes and binds promoters via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) . The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 . TAF13, together with TAF11 and TBP, play key roles during promoter binding by the TFIID and TFIIA transcription factor complexes . .

AccessionsA0A8J9AJQ9
Q0VA92
Q15543
ENST00000338366.6
ENST00000692048.1
ENST00000461096.7
A0A8I5KR19