TACR2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TACR2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TACR2 at tissue level.

III. Associated gene sets

GO_0014057Biological processpositive regulation of acetylcholine secretion, neurotransmission
GO_1902093Biological processpositive regulation of flagellated sperm motility
GO_0051602Biological processresponse to electrical stimulus
GO_0007217Biological processtachykinin receptor signaling pathway
GO_0033685Biological processnegative regulation of luteinizing hormone secretion
GO_0043270Biological processpositive regulation of monoatomic ion transport
GO_0006936Biological processmuscle contraction
GO_0070459Biological processprolactin secretion
GO_0045987Biological processpositive regulation of smooth muscle contraction
GO_0070474Biological processpositive regulation of uterine smooth muscle contraction
GO_0014827Biological processintestine smooth muscle contraction
GO_0035106Biological processoperant conditioning
GO_0043117Biological processpositive regulation of vascular permeability
GO_0061827Cellular componentsperm head
GO_0036126Cellular componentsperm flagellum
GO_0005886Cellular componentplasma membrane
GO_0097225Cellular componentsperm midpiece
GO_0016497Molecular functionsubstance K receptor activity
GO_0004995Molecular functiontachykinin receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTACR2
Protein nameSubstance-K receptor (NK-2 receptor) (Neurokinin A receptor) (Tachykinin receptor 2)
Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2)
SynonymsNK2R
TAC2R
NKNAR
DescriptionFUNCTION: This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. .

AccessionsENST00000373306.5
ENST00000373307.5
P21452
A6NEW7