Insufficient scRNA-seq data for expression of TACR2 at single-cell level.
Insufficient scRNA-seq data for expression of TACR2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 95% | 4684.75 | 1369 / 1445 | 69% | 4.41 | 126 / 183 |
uterus | 92% | 2003.07 | 157 / 170 | 64% | 4.60 | 294 / 459 |
intestine | 91% | 10398.75 | 877 / 966 | 64% | 4.95 | 336 / 527 |
prostate | 57% | 551.18 | 139 / 245 | 83% | 3.12 | 419 / 502 |
bladder | 86% | 3119.76 | 18 / 21 | 46% | 2.79 | 230 / 504 |
stomach | 51% | 3462.08 | 184 / 359 | 64% | 10.94 | 183 / 286 |
ovary | 24% | 79.14 | 44 / 180 | 78% | 2.93 | 336 / 430 |
eye | 0% | 0 | 0 / 0 | 98% | 4.86 | 78 / 80 |
skin | 10% | 26.10 | 179 / 1809 | 78% | 2.22 | 366 / 472 |
tonsil | 0% | 0 | 0 / 0 | 69% | 2.32 | 31 / 45 |
breast | 5% | 12.82 | 21 / 459 | 60% | 1.42 | 673 / 1118 |
lung | 6% | 13.10 | 33 / 578 | 49% | 4.44 | 563 / 1155 |
pancreas | 0% | 0 | 0 / 328 | 36% | 4.83 | 64 / 178 |
muscle | 33% | 84.47 | 265 / 803 | 0% | 0 | 0 / 0 |
brain | 9% | 17.56 | 230 / 2642 | 24% | 0.40 | 169 / 705 |
adrenal gland | 0% | 0 | 0 / 258 | 22% | 0.48 | 50 / 230 |
kidney | 0% | 0 | 0 / 89 | 20% | 0.30 | 180 / 901 |
heart | 16% | 35.17 | 134 / 861 | 0% | 0 | 0 / 0 |
thymus | 1% | 1.38 | 4 / 653 | 11% | 0.19 | 66 / 605 |
liver | 0% | 0 | 0 / 226 | 11% | 0.32 | 44 / 406 |
blood vessel | 8% | 18.76 | 105 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 0.11 | 2 / 29 |
adipose | 4% | 8.84 | 52 / 1204 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0014057 | Biological process | positive regulation of acetylcholine secretion, neurotransmission |
GO_1902093 | Biological process | positive regulation of flagellated sperm motility |
GO_0051602 | Biological process | response to electrical stimulus |
GO_0007217 | Biological process | tachykinin receptor signaling pathway |
GO_0033685 | Biological process | negative regulation of luteinizing hormone secretion |
GO_0043270 | Biological process | positive regulation of monoatomic ion transport |
GO_0006936 | Biological process | muscle contraction |
GO_0070459 | Biological process | prolactin secretion |
GO_0045987 | Biological process | positive regulation of smooth muscle contraction |
GO_0070474 | Biological process | positive regulation of uterine smooth muscle contraction |
GO_0014827 | Biological process | intestine smooth muscle contraction |
GO_0035106 | Biological process | operant conditioning |
GO_0043117 | Biological process | positive regulation of vascular permeability |
GO_0061827 | Cellular component | sperm head |
GO_0036126 | Cellular component | sperm flagellum |
GO_0005886 | Cellular component | plasma membrane |
GO_0097225 | Cellular component | sperm midpiece |
GO_0016497 | Molecular function | substance K receptor activity |
GO_0004995 | Molecular function | tachykinin receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | TACR2 |
Protein name | Substance-K receptor (NK-2 receptor) (Neurokinin A receptor) (Tachykinin receptor 2) Substance-K receptor (SKR) (NK-2 receptor) (NK-2R) (Neurokinin A receptor) (Tachykinin receptor 2) |
Synonyms | NK2R TAC2R NKNAR |
Description | FUNCTION: This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P. . |
Accessions | ENST00000373306.5 ENST00000373307.5 P21452 A6NEW7 |