SYNPO report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0032233Biological processpositive regulation of actin filament bundle assembly
GO_0098886Biological processmodification of dendritic spine
GO_1905355Biological processspine apparatus assembly
GO_0043204Cellular componentperikaryon
GO_0097444Cellular componentspine apparatus
GO_0001725Cellular componentstress fiber
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0043197Cellular componentdendritic spine
GO_0005886Cellular componentplasma membrane
GO_0014069Cellular componentpostsynaptic density
GO_0030018Cellular componentZ disc
GO_0005923Cellular componentbicellular tight junction
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameSYNPO
Protein nameSYNPO protein
Synaptopodin
Alternative protein SYNPO
SynonymsKIAA1029
DescriptionFUNCTION: Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity). .

AccessionsQ8N3V7
ENST00000394243.5 [Q8N3V7-1]
A7MD96
L8EC77
ENST00000519664.1 [Q8N3V7-3]
ENST00000522122.1 [Q8N3V7-1]
ENST00000307662.5 [Q8N3V7-2]