SYNJ2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0048488Biological processsynaptic vesicle endocytosis
GO_0061024Biological processmembrane organization
GO_0046856Biological processphosphatidylinositol dephosphorylation
GO_0036092Biological processphosphatidylinositol-3-phosphate biosynthetic process
GO_0006661Biological processphosphatidylinositol biosynthetic process
GO_0098793Cellular componentpresynapse
GO_0005856Cellular componentcytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0045121Cellular componentmembrane raft
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005829Cellular componentcytosol
GO_0042995Cellular componentcell projection
GO_0004438Molecular functionphosphatidylinositol-3-phosphate phosphatase activity
GO_0004439Molecular functionphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO_0030165Molecular functionPDZ domain binding
GO_0034596Molecular functionphosphatidylinositol phosphate 4-phosphatase activity
GO_0052629Molecular functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
GO_0003723Molecular functionRNA binding
GO_0043813Molecular functionphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
GO_0005515Molecular functionprotein binding
GO_0017124Molecular functionSH3 domain binding

IV. Literature review

[source]
Gene nameSYNJ2
Protein namephosphoinositide 5-phosphatase (EC 3.1.3.36)
Phosphatidylinositol-3-phosphatase SAC1 (EC 3.1.3.64) (Phosphatidylinositol-4-phosphate phosphatase) (Suppressor of actin mutations 1-like protein)
Synaptojanin 2
Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2)
SynonymsKIAA0348
DescriptionFUNCTION: Inositol 5-phosphatase which may be involved in distinct membrane trafficking and signal transduction pathways. May mediate the inhibitory effect of Rac1 on endocytosis.

AccessionsH0YEV8
O15056
ENST00000640338.1 [O15056-3]
ENST00000367122.6
ENST00000449320.2
ENST00000367113.5
A0A1W2PR85
Q5TA15
ENST00000485863.1
ENST00000355585.9 [O15056-1]
ENST00000638626.1
H7BY56
E7ER60