I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 3 studies | 19% ± 4% | |
| astrocyte | 3 studies | 24% ± 5% | |
| glutamatergic neuron | 3 studies | 26% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| cardiac muscle cell | 3 studies | 19% ± 4% | |
| astrocyte | 3 studies | 24% ± 5% | |
| glutamatergic neuron | 3 studies | 26% ± 4% |
Insufficient scRNA-seq data for expression of SYCP3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 87% | 5.55 | 1256 / 1445 | 30% | 0.60 | 54 / 183 |
| stomach | 92% | 6.86 | 331 / 359 | 18% | 0.46 | 51 / 286 |
| thymus | 95% | 8.05 | 623 / 653 | 10% | 0.14 | 58 / 605 |
| breast | 89% | 9.29 | 410 / 459 | 14% | 0.49 | 152 / 1118 |
| lung | 93% | 9.24 | 536 / 578 | 7% | 0.22 | 85 / 1155 |
| intestine | 93% | 8.47 | 903 / 966 | 6% | 0.16 | 32 / 527 |
| spleen | 98% | 11.85 | 235 / 241 | 0% | 0 | 0 / 0 |
| prostate | 94% | 12.35 | 231 / 245 | 2% | 0.05 | 8 / 502 |
| kidney | 91% | 7.04 | 81 / 89 | 2% | 0.10 | 20 / 901 |
| brain | 90% | 10.68 | 2385 / 2642 | 1% | 0.05 | 8 / 705 |
| ovary | 84% | 5.82 | 151 / 180 | 1% | 0.01 | 4 / 430 |
| uterus | 84% | 5.29 | 142 / 170 | 1% | 0.01 | 3 / 459 |
| adrenal gland | 84% | 4.59 | 217 / 258 | 0% | 0 | 0 / 230 |
| pancreas | 80% | 4.10 | 263 / 328 | 2% | 0.06 | 3 / 178 |
| blood vessel | 80% | 4.64 | 1071 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 79% | 4.21 | 952 / 1204 | 0% | 0 | 0 / 0 |
| heart | 79% | 3.97 | 677 / 861 | 0% | 0 | 0 / 0 |
| skin | 77% | 4.37 | 1384 / 1809 | 1% | 0.01 | 4 / 472 |
| bladder | 71% | 4.81 | 15 / 21 | 3% | 0.17 | 13 / 504 |
| peripheral blood | 70% | 4.96 | 646 / 929 | 0% | 0 | 0 / 0 |
| liver | 67% | 3.22 | 152 / 226 | 0% | 0.00 | 1 / 406 |
| muscle | 67% | 3.63 | 538 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0051321 | Biological process | meiotic cell cycle |
| GO_0035092 | Biological process | sperm DNA condensation |
| GO_0051301 | Biological process | cell division |
| GO_0007286 | Biological process | spermatid development |
| GO_0007141 | Biological process | male meiosis I |
| GO_0000775 | Cellular component | chromosome, centromeric region |
| GO_0000800 | Cellular component | lateral element |
| GO_0000795 | Cellular component | synaptonemal complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SYCP3 |
| Protein name | Synaptonemal complex protein 3 Synaptonemal complex protein 3 (SCP-3) |
| Synonyms | SCP3 |
| Description | FUNCTION: Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells (By similarity). Required for normal meiosis during spermatogenesis and male fertility . Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity). . |
| Accessions | ENST00000266743.6 A0A515MFP5 ENST00000392924.2 Q8IZU3 ENST00000392927.7 |
