Insufficient scRNA-seq data for expression of SYCE3 at single-cell level.
Insufficient scRNA-seq data for expression of SYCE3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 90% | 17.16 | 586 / 653 | 97% | 6.80 | 589 / 605 |
| brain | 93% | 17.68 | 2452 / 2642 | 83% | 3.34 | 588 / 705 |
| kidney | 93% | 32.79 | 83 / 89 | 78% | 4.35 | 707 / 901 |
| liver | 84% | 12.05 | 189 / 226 | 74% | 3.28 | 302 / 406 |
| breast | 68% | 8.98 | 310 / 459 | 89% | 7.10 | 997 / 1118 |
| lung | 57% | 4.89 | 328 / 578 | 78% | 3.86 | 900 / 1155 |
| adrenal gland | 83% | 14.95 | 213 / 258 | 31% | 1.01 | 71 / 230 |
| prostate | 53% | 5.94 | 131 / 245 | 56% | 1.82 | 279 / 502 |
| pancreas | 35% | 2.63 | 115 / 328 | 67% | 1.94 | 120 / 178 |
| skin | 47% | 3.66 | 842 / 1809 | 56% | 1.95 | 262 / 472 |
| esophagus | 40% | 3.10 | 581 / 1445 | 61% | 1.43 | 111 / 183 |
| uterus | 15% | 0.94 | 26 / 170 | 72% | 3.20 | 331 / 459 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 2.63 | 39 / 45 |
| ovary | 6% | 0.24 | 11 / 180 | 80% | 4.28 | 345 / 430 |
| stomach | 30% | 1.88 | 106 / 359 | 53% | 1.20 | 152 / 286 |
| intestine | 31% | 2.10 | 300 / 966 | 45% | 1.22 | 237 / 527 |
| eye | 0% | 0 | 0 / 0 | 73% | 1.92 | 58 / 80 |
| bladder | 10% | 0.48 | 2 / 21 | 63% | 1.97 | 317 / 504 |
| peripheral blood | 57% | 8.10 | 530 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 48% | 1.43 | 14 / 29 |
| adipose | 44% | 2.92 | 526 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 41% | 2.77 | 99 / 241 | 0% | 0 | 0 / 0 |
| heart | 29% | 1.78 | 248 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 11% | 0.53 | 145 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 6% | 0.55 | 50 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007131 | Biological process | reciprocal meiotic recombination |
| GO_0006915 | Biological process | apoptotic process |
| GO_2000243 | Biological process | positive regulation of reproductive process |
| GO_0007130 | Biological process | synaptonemal complex assembly |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0051301 | Biological process | cell division |
| GO_0051094 | Biological process | positive regulation of developmental process |
| GO_0043065 | Biological process | positive regulation of apoptotic process |
| GO_0035234 | Biological process | ectopic germ cell programmed cell death |
| GO_0000801 | Cellular component | central element |
| GO_0005694 | Cellular component | chromosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SYCE3 |
| Protein name | Synaptonemal complex central element protein 3 (Testis highly expressed gene 2 protein) (THEG-2) |
| Synonyms | THEG2 C22orf41 |
| Description | FUNCTION: Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for chromosome loading of the central element-specific SCS proteins, and for initiating synapsis between homologous chromosomes. Chromosome loading appears to require SYCP1. Required for fertility. . |
| Accessions | ENST00000402753.1 A1L190 ENST00000406915.4 |