Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 6 studies | 26% ± 10% | |
ciliated cell | 5 studies | 24% ± 6% |
Insufficient scRNA-seq data for expression of STK16 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 100% | 1578.02 | 226 / 226 | 100% | 21.26 | 406 / 406 |
ovary | 100% | 1154.37 | 180 / 180 | 100% | 22.17 | 430 / 430 |
pancreas | 100% | 1292.67 | 328 / 328 | 100% | 23.92 | 178 / 178 |
stomach | 100% | 1445.00 | 359 / 359 | 100% | 19.28 | 286 / 286 |
thymus | 100% | 1707.07 | 653 / 653 | 100% | 29.45 | 605 / 605 |
brain | 100% | 1025.34 | 2639 / 2642 | 100% | 24.85 | 705 / 705 |
lung | 100% | 1257.78 | 577 / 578 | 100% | 22.43 | 1154 / 1155 |
kidney | 100% | 1652.35 | 89 / 89 | 100% | 26.88 | 898 / 901 |
breast | 100% | 1406.78 | 459 / 459 | 100% | 27.61 | 1114 / 1118 |
intestine | 100% | 1481.59 | 966 / 966 | 100% | 23.32 | 525 / 527 |
prostate | 100% | 1557.64 | 245 / 245 | 100% | 29.22 | 500 / 502 |
skin | 100% | 1451.94 | 1809 / 1809 | 100% | 23.44 | 470 / 472 |
uterus | 100% | 1163.40 | 170 / 170 | 100% | 18.52 | 457 / 459 |
esophagus | 100% | 1355.00 | 1445 / 1445 | 99% | 12.86 | 182 / 183 |
bladder | 100% | 1336.00 | 21 / 21 | 99% | 20.60 | 501 / 504 |
adrenal gland | 100% | 1835.73 | 258 / 258 | 97% | 15.63 | 224 / 230 |
adipose | 100% | 1181.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 30.25 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 29.74 | 29 / 29 |
spleen | 100% | 1756.91 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 20.01 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 14.40 | 1 / 1 |
blood vessel | 100% | 1150.10 | 1334 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 2000.42 | 923 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 811.80 | 843 / 861 | 0% | 0 | 0 / 0 |
muscle | 97% | 626.21 | 775 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0071560 | Biological process | cellular response to transforming growth factor beta stimulus |
GO_0046777 | Biological process | protein autophosphorylation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005798 | Cellular component | Golgi-associated vesicle |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005886 | Cellular component | plasma membrane |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005737 | Cellular component | cytoplasm |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0004715 | Molecular function | non-membrane spanning protein tyrosine kinase activity |
GO_0005524 | Molecular function | ATP binding |
GO_0004674 | Molecular function | protein serine/threonine kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0106310 | Molecular function | protein serine kinase activity |
Gene name | STK16 |
Protein name | non-specific serine/threonine protein kinase (EC 2.7.11.1) Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK) |
Synonyms | MPSK1 TSF1 PKL12 |
Description | FUNCTION: Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins. . |
Accessions | B8ZZN3 ENST00000409743.1 B8ZZI5 B4DPS1 ENST00000409516.7 ENST00000396738.7 ENST00000409260.5 O75716 ENST00000409638.7 |