STAG3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0034089Biological processestablishment of meiotic sister chromatid cohesion
GO_0007062Biological processsister chromatid cohesion
GO_0007130Biological processsynaptonemal complex assembly
GO_0030893Cellular componentmeiotic cohesin complex
GO_0000775Cellular componentchromosome, centromeric region
GO_0005730Cellular componentnucleolus
GO_0005615Cellular componentextracellular space
GO_0000795Cellular componentsynaptonemal complex
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003682Molecular functionchromatin binding

IV. Literature review

[source]
Gene nameSTAG3
Protein nameCohesin subunit SA (SCC3 homolog) (Stromal antigen)
Cohesin subunit SA-3 (SCC3 homolog 3) (Stromal antigen 3) (Stromalin-3)
Stromal antigen 3
SynonymshCG_2024106
DescriptionFUNCTION: Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I. .

FUNCTION: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. .

FUNCTION: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. .

AccessionsQ9UJ98
ENST00000416412.5
ENST00000422690.5
H7C0H6
ENST00000426455.5 [Q9UJ98-1]
ENST00000615138.5
ENST00000412190.6
ENST00000317296.9 [Q9UJ98-1]
ENST00000439782.1
C9JYW5
ENST00000394018.6 [Q9UJ98-3]
C9J3T3
D6W5U7
C9JTG4
B2RU25
ENST00000620100.5 [Q9UJ98-3]