STAC | OmnibusX

Name	Number of supported studies	Average coverage
Mueller cell	4 studies	24% ± 7%	Explore
alveolar macrophage	4 studies	44% ± 14%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of STAC at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	85%	299.84	220 / 258	88%	18.90	203 / 230
prostate	97%	1115.78	238 / 245	72%	4.29	363 / 502
lung	100%	782.92	577 / 578	65%	3.88	754 / 1155
kidney	100%	347.09	89 / 89	56%	2.76	503 / 901
breast	93%	288.61	426 / 459	45%	2.56	507 / 1118
uterus	91%	329.11	155 / 170	41%	4.40	186 / 459
ovary	63%	104.80	113 / 180	60%	2.40	257 / 430
bladder	90%	570.05	19 / 21	30%	1.26	151 / 504
esophagus	70%	203.78	1009 / 1445	46%	2.17	84 / 183
thymus	43%	64.00	278 / 653	63%	4.28	383 / 605
blood vessel	97%	926.07	1300 / 1335	0%	0	0 / 0
skin	78%	198.21	1411 / 1809	15%	0.65	70 / 472
brain	55%	264.82	1447 / 2642	34%	4.16	242 / 705
adipose	85%	315.40	1028 / 1204	0%	0	0 / 0
intestine	66%	289.62	639 / 966	18%	0.57	97 / 527
muscle	68%	126.32	546 / 803	0%	0	0 / 0
pancreas	1%	1.11	4 / 328	63%	2.53	112 / 178
stomach	38%	115.37	138 / 359	22%	0.67	62 / 286
liver	38%	52.50	86 / 226	13%	0.63	51 / 406
tonsil	0%	0	0 / 0	33%	2.62	15 / 45
lymph node	0%	0	0 / 0	24%	0.36	7 / 29
spleen	19%	22.63	45 / 241	0%	0	0 / 0
heart	15%	19.60	130 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	4%	0.12	3 / 80
peripheral blood	2%	3.68	23 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_2001259	Biological process	positive regulation of cation channel activity
GO_1903078	Biological process	positive regulation of protein localization to plasma membrane
GO_1901387	Biological process	positive regulation of voltage-gated calcium channel activity
GO_0003009	Biological process	skeletal muscle contraction
GO_0034605	Biological process	cellular response to heat
GO_0009898	Cellular component	cytoplasmic side of plasma membrane
GO_0030315	Cellular component	T-tubule
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding
GO_0046872	Molecular function	metal ion binding
GO_0044325	Molecular function	transmembrane transporter binding

Gene name	STAC
Protein name	SH3 and cysteine rich domain SH3 and cysteine-rich domain-containing protein (Src homology 3 and cysteine-rich domain-containing protein)
Synonyms	STAC1
Description	FUNCTION: Promotes expression of the ion channel CACNA1H at the cell membrane, and thereby contributes to the regulation of channel activity. Plays a minor and redundant role in promoting the expression of calcium channel CACNA1S at the cell membrane, and thereby contributes to increased channel activity. Slows down the inactivation rate of the calcium channel CACNA1C. .
Accessions	E9PEA7 ENST00000427486.5 ENST00000273183.8 ENST00000434649.1 F8WB25 Q99469 Q8WUK8 C9J3Z9 ENST00000457375.6

STAC report