ST18 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010468Biological processregulation of gene expression
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0070102Biological processinterleukin-6-mediated signaling pathway
GO_0070498Biological processinterleukin-1-mediated signaling pathway
GO_2001269Biological processpositive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO_0033209Biological processtumor necrosis factor-mediated signaling pathway
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0032993Cellular componentprotein-DNA complex
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0008270Molecular functionzinc ion binding

IV. Literature review

[source]
Gene nameST18
Protein nameSuppression of tumorigenicity 18 protein (Zinc finger protein 387)
ST18 C2H2C-type zinc finger transcription factor
Alternative protein ST18
SynonymsKIAA0535
ZNF387
DescriptionFUNCTION: Repressor that binds to DNA sequences containing a bipartite element consisting of a direct repeat of the sequence 5'-AAAGTTT-3' separated by 2-9 nucleotides. Represses basal transcription activity from target promoters (By similarity). Inhibits colony formation in cultured breast cancer cells. .

AccessionsE5RFE8
ENST00000521824.5
E5RHS3
O60284
E5RK88
L8E831
ENST00000521582.5
ENST00000522251.5
ENST00000276480.11
ENST00000693301.1
ENST00000699087.1
E5RID0
ENST00000519118.5
E5RHY1
ENST00000689386.1
ENST00000517580.5