SPTA1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SPTA1 at tissue level.

III. Associated gene sets

GO_0042102Biological processpositive regulation of T cell proliferation
GO_0030097Biological processhemopoiesis
GO_0002260Biological processlymphocyte homeostasis
GO_0051693Biological processactin filament capping
GO_0006779Biological processporphyrin-containing compound biosynthetic process
GO_0030036Biological processactin cytoskeleton organization
GO_0007009Biological processplasma membrane organization
GO_0007015Biological processactin filament organization
GO_0008360Biological processregulation of cell shape
GO_0005886Cellular componentplasma membrane
GO_0009898Cellular componentcytoplasmic side of plasma membrane
GO_0030864Cellular componentcortical actin cytoskeleton
GO_0014731Cellular componentspectrin-associated cytoskeleton
GO_0032437Cellular componentcuticular plate
GO_0015629Cellular componentactin cytoskeleton
GO_0005829Cellular componentcytosol
GO_0042995Cellular componentcell projection
GO_0030054Cellular componentcell junction
GO_0030424Cellular componentaxon
GO_0008091Cellular componentspectrin
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0051015Molecular functionactin filament binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSPTA1
Protein nameAlternative protein SPTA1
Erythroid alpha-spectrin
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
SynonymsSPTA
DescriptionFUNCTION: Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane.

AccessionsL8E8Z3
P02549
ENST00000643759.2 [P02549-1]
O60686