Name | Number of supported studies | Average coverage | |
---|---|---|---|
erythrocyte | 5 studies | 57% ± 23% | |
erythroblast | 3 studies | 35% ± 21% |
Insufficient scRNA-seq data for expression of SPTA1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
spleen | 99% | 504.26 | 239 / 241 | 0% | 0 | 0 / 0 |
breast | 90% | 69.77 | 412 / 459 | 0% | 0.01 | 3 / 1118 |
peripheral blood | 90% | 632.97 | 834 / 929 | 0% | 0 | 0 / 0 |
adipose | 88% | 73.24 | 1059 / 1204 | 0% | 0 | 0 / 0 |
lung | 83% | 80.11 | 481 / 578 | 1% | 0.03 | 13 / 1155 |
liver | 55% | 35.18 | 125 / 226 | 4% | 0.24 | 17 / 406 |
muscle | 52% | 16.95 | 416 / 803 | 0% | 0 | 0 / 0 |
uterus | 48% | 17.56 | 82 / 170 | 1% | 0.01 | 3 / 459 |
thymus | 46% | 14.54 | 301 / 653 | 1% | 0.02 | 6 / 605 |
kidney | 43% | 17.13 | 38 / 89 | 2% | 0.06 | 14 / 901 |
heart | 43% | 13.03 | 370 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 40% | 12.05 | 534 / 1335 | 0% | 0 | 0 / 0 |
bladder | 38% | 11.52 | 8 / 21 | 1% | 0.11 | 6 / 504 |
skin | 19% | 6.41 | 350 / 1809 | 16% | 0.55 | 74 / 472 |
ovary | 33% | 8.93 | 59 / 180 | 0% | 0.00 | 1 / 430 |
adrenal gland | 24% | 5.19 | 62 / 258 | 1% | 0.05 | 3 / 230 |
intestine | 23% | 6.28 | 224 / 966 | 0% | 0.00 | 1 / 527 |
esophagus | 22% | 7.90 | 325 / 1445 | 1% | 0.02 | 1 / 183 |
prostate | 14% | 3.33 | 34 / 245 | 0% | 0 | 0 / 502 |
stomach | 9% | 2.40 | 31 / 359 | 1% | 0.01 | 3 / 286 |
brain | 9% | 2.39 | 232 / 2642 | 0% | 0 | 0 / 705 |
pancreas | 5% | 0.73 | 16 / 328 | 0% | 0 | 0 / 178 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042102 | Biological process | positive regulation of T cell proliferation |
GO_0030097 | Biological process | hemopoiesis |
GO_0002260 | Biological process | lymphocyte homeostasis |
GO_0051693 | Biological process | actin filament capping |
GO_0006779 | Biological process | porphyrin-containing compound biosynthetic process |
GO_0030036 | Biological process | actin cytoskeleton organization |
GO_0007009 | Biological process | plasma membrane organization |
GO_0007015 | Biological process | actin filament organization |
GO_0008360 | Biological process | regulation of cell shape |
GO_0005886 | Cellular component | plasma membrane |
GO_0009898 | Cellular component | cytoplasmic side of plasma membrane |
GO_0030864 | Cellular component | cortical actin cytoskeleton |
GO_0014731 | Cellular component | spectrin-associated cytoskeleton |
GO_0032437 | Cellular component | cuticular plate |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0042995 | Cellular component | cell projection |
GO_0030054 | Cellular component | cell junction |
GO_0030424 | Cellular component | axon |
GO_0008091 | Cellular component | spectrin |
GO_0005200 | Molecular function | structural constituent of cytoskeleton |
GO_0051015 | Molecular function | actin filament binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SPTA1 |
Protein name | Alternative protein SPTA1 Erythroid alpha-spectrin Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin) |
Synonyms | SPTA |
Description | FUNCTION: Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. |
Accessions | L8E8Z3 P02549 ENST00000643759.2 [P02549-1] O60686 |