SPOUT1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SPOUT1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SPOUT1 at tissue level.

III. Associated gene sets

GO_0035196Biological processmiRNA processing
GO_0051301Biological processcell division
GO_0010608Biological processpost-transcriptional regulation of gene expression
GO_0032259Biological processmethylation
GO_0051661Biological processmaintenance of centrosome location
GO_0000776Cellular componentkinetochore
GO_0072686Cellular componentmitotic spindle
GO_0005737Cellular componentcytoplasm
GO_0031616Cellular componentspindle pole centrosome
GO_0008168Molecular functionmethyltransferase activity
GO_0035198Molecular functionmiRNA binding
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameSPOUT1
Protein namePutative methyltransferase C9orf114 (EC 2.1.1.-) (Centromere protein 32) (CENP-32) (Kinetochore-associated protein) (SPOUT domain-containing methyltransferase 1)
SPOUT domain containing methyltransferase 1
SynonymsC9orf114
DescriptionFUNCTION: Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase . Also involved in chromosome alignment . May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis . Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level . .

AccessionsENST00000361256.10
Q5T280
R4GNG4
ENST00000467582.1