SPON1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1902430Biological processnegative regulation of amyloid-beta formation
GO_0016485Biological processprotein processing
GO_0007155Biological processcell adhesion
GO_1902993Biological processpositive regulation of amyloid precursor protein catabolic process
GO_0010954Biological processpositive regulation of protein processing
GO_0005615Cellular componentextracellular space
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0031012Cellular componentextracellular matrix
GO_0005201Molecular functionextracellular matrix structural constituent
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding
GO_0050693Molecular functionLBD domain binding

IV. Literature review

[source]
Gene nameSPON1
Protein nameSpondin-1 (F-spondin) (Vascular smooth muscle cell growth-promoting factor)
SPON1 protein
SynonymsVSGP
KIAA0762
DescriptionFUNCTION: Cell adhesion protein that promotes the attachment of spinal cord and sensory neuron cells and the outgrowth of neurites in vitro. May contribute to the growth and guidance of axons in both the spinal cord and the PNS (By similarity). Major factor for vascular smooth muscle cell. .

AccessionsQ3ZCT3
ENST00000576479.4
Q9HCB6