SPATA33 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SPATA33 at tissue level.

III. Associated gene sets

GO_0000423Biological processmitophagy
GO_0097225Cellular componentsperm midpiece
GO_0005829Cellular componentcytosol
GO_0097226Cellular componentsperm mitochondrial sheath
GO_0005737Cellular componentcytoplasm
GO_0005739Cellular componentmitochondrion
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSPATA33
Protein nameSpermatogenesis-associated protein 33
Spermatogenesis associated 33
SynonymsC16orf55
DescriptionFUNCTION: Plays an important role in sperm motility and male fertility (By similarity). Required for sperm midpiece flexibility and for the localization of sperm calcineurin to the mitochondria (By similarity). Promotes mitophagy as well as acts as an autophagy mediator in male germline cells (By similarity). Links damaged mitochondria to autophagosomes via its binding to the outer mitochondrial membrane protein VDAC2, as well as to key autophagy machinery component ATG16L1 (By similarity). .

AccessionsENST00000611218.1
J3KSB2
H3BQG0
ENST00000579310.6 [Q96N06-2]
ENST00000457689.3
ENST00000566204.2
ENST00000301031.8 [Q96N06-1]
J3KS00
H3BSG8
ENST00000564238.2
ENST00000568929.1
ENST00000565890.1
Q96N06
ENST00000567827.1
J3KRC8
J3KS58