SNCG report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0008344Biological processadult locomotory behavior
GO_0048488Biological processsynaptic vesicle endocytosis
GO_0014059Biological processregulation of dopamine secretion
GO_0007268Biological processchemical synaptic transmission
GO_0050808Biological processsynapse organization
GO_0046928Biological processregulation of neurotransmitter secretion
GO_0009306Biological processprotein secretion
GO_0005813Cellular componentcentrosome
GO_0070062Cellular componentextracellular exosome
GO_0043679Cellular componentaxon terminus
GO_0043025Cellular componentneuronal cell body
GO_0005819Cellular componentspindle
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005737Cellular componentcytoplasm
GO_1903136Molecular functioncuprous ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSNCG
Protein nameSynuclein gamma
Gamma-synuclein
Gamma-synuclein (Breast cancer-specific gene 1 protein) (Persyn) (Synoretin) (SR)
SynonymsBCSG1
PRSN
PERSYN
hCG_23263
DescriptionFUNCTION: Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity). .

AccessionsENST00000372017.4
A9XXE1
ENST00000348795.8
F8W754
Q6FHG5
O76070