Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 8 studies | 42% ± 14% | |
| GABAergic neuron | 5 studies | 33% ± 9% | |
| amacrine cell | 5 studies | 53% ± 22% | |
| OFF-bipolar cell | 4 studies | 57% ± 28% | |
| ON-bipolar cell | 4 studies | 46% ± 31% | |
| retinal ganglion cell | 4 studies | 80% ± 27% | |
| retinal cone cell | 4 studies | 53% ± 22% | |
| retina horizontal cell | 4 studies | 39% ± 13% | |
| retinal rod cell | 4 studies | 31% ± 11% | |
| neuron | 3 studies | 37% ± 14% | |
| retinal bipolar neuron | 3 studies | 39% ± 16% | |
| GABAergic amacrine cell | 3 studies | 61% ± 16% | |
| glycinergic amacrine cell | 3 studies | 38% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 95% | 16027.65 | 2513 / 2642 | 97% | 107.84 | 681 / 705 |
| eye | 0% | 0 | 0 / 0 | 83% | 14.33 | 66 / 80 |
| adrenal gland | 1% | 14.64 | 2 / 258 | 77% | 28.88 | 176 / 230 |
| skin | 0% | 0.46 | 1 / 1809 | 32% | 4.95 | 149 / 472 |
| pancreas | 0% | 0 | 0 / 328 | 18% | 1.82 | 32 / 178 |
| ovary | 0% | 0 | 0 / 180 | 14% | 1.15 | 62 / 430 |
| esophagus | 0% | 0 | 0 / 1445 | 11% | 0.83 | 21 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 11% | 0.35 | 5 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.37 | 3 / 29 |
| uterus | 0% | 0 | 0 / 170 | 9% | 1.25 | 40 / 459 |
| lung | 0% | 0 | 0 / 578 | 7% | 0.33 | 83 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 2% | 0.21 | 12 / 504 |
| kidney | 0% | 0 | 0 / 89 | 2% | 0.94 | 19 / 901 |
| intestine | 0% | 0 | 0 / 966 | 1% | 0.05 | 6 / 527 |
| stomach | 0% | 0 | 0 / 359 | 1% | 0.03 | 3 / 286 |
| breast | 0% | 0 | 0 / 459 | 1% | 0.09 | 11 / 1118 |
| thymus | 0% | 0 | 0 / 653 | 1% | 0.10 | 5 / 605 |
| prostate | 0% | 0 | 0 / 245 | 1% | 0.06 | 4 / 502 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.62 | 3 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0048488 | Biological process | synaptic vesicle endocytosis |
| GO_0051402 | Biological process | neuron apoptotic process |
| GO_0042417 | Biological process | dopamine metabolic process |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0050808 | Biological process | synapse organization |
| GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
| GO_0016234 | Cellular component | inclusion body |
| GO_0043679 | Cellular component | axon terminus |
| GO_0005829 | Cellular component | cytosol |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0005737 | Cellular component | cytoplasm |
| GO_1903136 | Molecular function | cuprous ion binding |
| GO_0004859 | Molecular function | phospholipase inhibitor activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0046914 | Molecular function | transition metal ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SNCB |
| Protein name | Beta-synuclein |
| Synonyms | |
| Description | FUNCTION: Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease. |
| Accessions | ENST00000506696.1 ENST00000393693.7 G4Y815 ENST00000614675.4 Q16143 G4Y816 ENST00000510387.5 ENST00000310112.7 |