SNCAIP | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	13 studies	30% ± 11%	Explore
interneuron	6 studies	31% ± 10%	Explore
glutamatergic neuron	5 studies	33% ± 12%	Explore
oligodendrocyte precursor cell	5 studies	19% ± 2%	Explore
GABAergic neuron	5 studies	38% ± 8%	Explore
endothelial cell of lymphatic vessel	4 studies	34% ± 11%	Explore
endothelial cell	3 studies	36% ± 20%	Explore
granule cell	3 studies	21% ± 5%	Explore
neuron	3 studies	29% ± 8%	Explore
mesothelial cell	3 studies	25% ± 6%	Explore
ciliated cell	3 studies	22% ± 4%	Explore

Name	Number of supported studies	Average coverage
brain	8 studies	25% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	95%	640.25	2508 / 2642	99%	17.59	699 / 705
uterus	100%	2677.19	170 / 170	78%	6.58	360 / 459
prostate	95%	765.42	233 / 245	77%	2.43	386 / 502
lung	79%	198.27	455 / 578	76%	3.35	874 / 1155
breast	96%	423.95	441 / 459	54%	1.69	606 / 1118
ovary	100%	3025.96	180 / 180	50%	1.53	215 / 430
intestine	81%	263.30	786 / 966	54%	2.15	283 / 527
esophagus	61%	134.41	883 / 1445	72%	4.22	132 / 183
bladder	67%	146.14	14 / 21	58%	2.45	294 / 504
thymus	82%	214.05	535 / 653	34%	1.55	207 / 605
stomach	52%	140.58	186 / 359	60%	3.63	171 / 286
spleen	100%	1219.52	241 / 241	0%	0	0 / 0
blood vessel	100%	801.21	1331 / 1335	0%	0	0 / 0
adipose	98%	781.18	1184 / 1204	0%	0	0 / 0
adrenal gland	62%	139.18	159 / 258	17%	0.91	38 / 230
kidney	56%	199.89	50 / 89	19%	0.65	168 / 901
pancreas	0%	0.55	1 / 328	74%	2.84	131 / 178
skin	64%	206.12	1163 / 1809	9%	0.54	42 / 472
tonsil	0%	0	0 / 0	64%	3.02	29 / 45
heart	46%	101.58	393 / 861	0%	0	0 / 0
liver	4%	5.33	8 / 226	22%	1.20	91 / 406
lymph node	0%	0	0 / 0	21%	0.99	6 / 29
muscle	8%	14.47	65 / 803	0%	0	0 / 0
peripheral blood	1%	2.98	10 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0090083	Biological process	regulation of inclusion body assembly
GO_0042417	Biological process	dopamine metabolic process
GO_0008219	Biological process	cell death
GO_0046928	Biological process	regulation of neurotransmitter secretion
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0008021	Cellular component	synaptic vesicle
GO_0043025	Cellular component	neuronal cell body
GO_0042734	Cellular component	presynaptic membrane
GO_0005737	Cellular component	cytoplasm
GO_0036464	Cellular component	cytoplasmic ribonucleoprotein granule
GO_0031625	Molecular function	ubiquitin protein ligase binding
GO_0005515	Molecular function	protein binding
GO_0042802	Molecular function	identical protein binding

Gene name	SNCAIP
Protein name	Synphilin-1e protein (Synuclein alpha interacting protein) Synuclein alpha interacting protein Synphilin-1g protein (Synuclein alpha interacting protein) Synphilin-1d protein (Synuclein alpha interacting protein) Synphilin-1f protein (Synuclein alpha interacting protein) Synphilin-1 (Sph1) (Alpha-synuclein-interacting protein)
Synonyms
Description	FUNCTION: Isoform 2 inhibits the ubiquitin ligase activity of SIAH1 and inhibits proteasomal degradation of target proteins. Isoform 2 inhibits autoubiquitination and proteasomal degradation of SIAH1, and thereby increases cellular levels of SIAH. Isoform 2 modulates SNCA monoubiquitination by SIAH1. .
Accessions	D6RFL3 ENST00000395469.6 [Q9Y6H5-6] D6RBR2 Q6L980 ENST00000512385.5 ENST00000510658.5 Q6L983 ENST00000261368.13 [Q9Y6H5-1] ENST00000395466.6 Q9Y6H5 ENST00000509154.6 ENST00000514467.5 ENST00000508681.5 ENST00000261367.11 [Q9Y6H5-3] ENST00000508017.5 D6RD29 D6R9G8 D6REC1 ENST00000509652.1 ENST00000542191.5 ENST00000506272.5 Q6L982 ENST00000514497.6 ENST00000509023.5 ENST00000515215.6 ENST00000512146.6 Q6L981 D6RHX3

SNCAIP report