I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 30% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 30% ± 2% |
Insufficient scRNA-seq data for expression of SNAI3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 96% | 114.61 | 2549 / 2642 | 99% | 4.43 | 696 / 705 |
| thymus | 95% | 82.49 | 621 / 653 | 99% | 4.12 | 598 / 605 |
| lung | 100% | 188.65 | 578 / 578 | 91% | 3.27 | 1048 / 1155 |
| prostate | 94% | 78.08 | 230 / 245 | 90% | 2.26 | 452 / 502 |
| pancreas | 84% | 68.44 | 276 / 328 | 95% | 4.33 | 169 / 178 |
| stomach | 92% | 178.44 | 331 / 359 | 78% | 2.57 | 222 / 286 |
| kidney | 72% | 55.69 | 64 / 89 | 94% | 3.04 | 846 / 901 |
| ovary | 78% | 40.28 | 141 / 180 | 86% | 2.17 | 368 / 430 |
| uterus | 75% | 40.49 | 128 / 170 | 83% | 3.59 | 380 / 459 |
| intestine | 79% | 114.04 | 767 / 966 | 77% | 2.28 | 404 / 527 |
| bladder | 86% | 112.43 | 18 / 21 | 66% | 2.32 | 334 / 504 |
| breast | 64% | 35.27 | 296 / 459 | 83% | 2.35 | 931 / 1118 |
| adrenal gland | 76% | 43.04 | 196 / 258 | 62% | 1.63 | 142 / 230 |
| esophagus | 63% | 33.98 | 916 / 1445 | 74% | 1.87 | 136 / 183 |
| skin | 40% | 18.17 | 718 / 1809 | 79% | 2.49 | 375 / 472 |
| liver | 56% | 26.38 | 127 / 226 | 52% | 1.24 | 210 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 9.73 | 29 / 29 |
| peripheral blood | 100% | 796.94 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 544.40 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 9.03 | 1 / 1 |
| muscle | 99% | 497.80 | 798 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 3.76 | 42 / 45 |
| heart | 84% | 90.71 | 722 / 861 | 0% | 0 | 0 / 0 |
| adipose | 81% | 51.83 | 970 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 48% | 32.16 | 644 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 43% | 0.69 | 34 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006355 | Biological process | regulation of DNA-templated transcription |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0005507 | Molecular function | copper ion binding |
| GO_0001227 | Molecular function | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Gene name | SNAI3 |
| Protein name | Zinc finger protein SNAI3 (Protein snail homolog 3) (Zinc finger protein 293) |
| Synonyms | ZNF293 |
| Description | FUNCTION: Seems to inhibit myoblast differentiation. Transcriptional repressor of E-box-dependent transactivation of downstream myogenic bHLHs genes. Binds preferentially to the canonical E-box sequences 5'-CAGGTG-3' and 5'-CACCTG-3' (By similarity). . |
| Accessions | Q3KNW1 ENST00000332281.6 |
