Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| T cell | 6 studies | 27% ± 5% | |
| B cell | 5 studies | 23% ± 4% | |
| plasmablast | 5 studies | 31% ± 16% | |
| endothelial cell | 5 studies | 22% ± 7% | |
| ciliated cell | 5 studies | 25% ± 15% | |
| natural killer cell | 5 studies | 27% ± 9% | |
| CD4-positive, alpha-beta T cell | 5 studies | 26% ± 6% | |
| hematopoietic precursor cell | 4 studies | 23% ± 7% | |
| epithelial cell | 4 studies | 31% ± 10% | |
| pro-B cell | 4 studies | 28% ± 7% | |
| basal cell | 4 studies | 22% ± 5% | |
| CD8-positive, alpha-beta T cell | 4 studies | 30% ± 3% | |
| connective tissue cell | 3 studies | 17% ± 0% | |
| abnormal cell | 3 studies | 19% ± 2% | |
| neural crest cell | 3 studies | 32% ± 10% | |
| neuron | 3 studies | 17% ± 0% | |
| GABAergic neuron | 3 studies | 23% ± 4% | |
| glutamatergic neuron | 3 studies | 26% ± 7% | |
| transit amplifying cell | 3 studies | 35% ± 10% | |
| erythroblast | 3 studies | 42% ± 21% | |
| effector CD8-positive, alpha-beta T cell | 3 studies | 24% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1037.30 | 1443 / 1445 | 100% | 37.42 | 183 / 183 |
| uterus | 100% | 853.36 | 170 / 170 | 99% | 33.25 | 454 / 459 |
| stomach | 100% | 717.48 | 358 / 359 | 99% | 24.70 | 283 / 286 |
| brain | 99% | 691.27 | 2623 / 2642 | 99% | 20.67 | 700 / 705 |
| breast | 100% | 958.27 | 459 / 459 | 99% | 24.29 | 1102 / 1118 |
| intestine | 100% | 923.64 | 966 / 966 | 98% | 23.91 | 519 / 527 |
| ovary | 100% | 705.71 | 180 / 180 | 98% | 14.86 | 423 / 430 |
| lung | 99% | 728.81 | 572 / 578 | 99% | 20.67 | 1143 / 1155 |
| thymus | 100% | 745.72 | 652 / 653 | 96% | 13.93 | 580 / 605 |
| bladder | 100% | 745.95 | 21 / 21 | 95% | 19.46 | 480 / 504 |
| skin | 100% | 2074.90 | 1809 / 1809 | 90% | 18.63 | 425 / 472 |
| prostate | 98% | 548.59 | 241 / 245 | 89% | 10.05 | 449 / 502 |
| pancreas | 91% | 327.80 | 298 / 328 | 94% | 10.69 | 167 / 178 |
| adrenal gland | 98% | 784.98 | 252 / 258 | 86% | 9.69 | 197 / 230 |
| kidney | 100% | 543.97 | 89 / 89 | 82% | 9.99 | 740 / 901 |
| liver | 85% | 304.53 | 192 / 226 | 62% | 5.90 | 250 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 29.09 | 29 / 29 |
| spleen | 100% | 1081.06 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 47.49 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.01 | 1 / 1 |
| blood vessel | 100% | 811.45 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 100% | 960.29 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 95% | 367.17 | 765 / 803 | 0% | 0 | 0 / 0 |
| heart | 93% | 730.22 | 803 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 55% | 1777.36 | 515 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 48% | 3.85 | 38 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_1905821 | Biological process | positive regulation of chromosome condensation |
| GO_0045132 | Biological process | meiotic chromosome segregation |
| GO_0010032 | Biological process | meiotic chromosome condensation |
| GO_0051301 | Biological process | cell division |
| GO_0051984 | Biological process | positive regulation of chromosome segregation |
| GO_1905820 | Biological process | positive regulation of chromosome separation |
| GO_0007076 | Biological process | mitotic chromosome condensation |
| GO_0051383 | Biological process | kinetochore organization |
| GO_0005730 | Cellular component | nucleolus |
| GO_0000228 | Cellular component | nuclear chromosome |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000796 | Cellular component | condensin complex |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0000794 | Cellular component | condensed nuclear chromosome |
| GO_0000793 | Cellular component | condensed chromosome |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0003697 | Molecular function | single-stranded DNA binding |
| GO_0005524 | Molecular function | ATP binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| Gene name | SMC2 |
| Protein name | Structural maintenance of chromosomes protein SMC2 protein Structural maintenance of chromosomes protein 2 (SMC protein 2) (SMC-2) (Chromosome-associated protein E) (hCAP-E) (XCAP-E homolog) Structural maintenance of chromosomes 2 |
| Synonyms | CAPE PRO0324 SMC2L1 |
| Description | FUNCTION: Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. . |
| Accessions | O95347 Q05D74 Q6IPS5 Q05BV1 A0A0C4DGE5 ENST00000286398.11 [O95347-1] B7ZLZ7 A0JLM9 ENST00000374793.8 [O95347-1] ENST00000493955.1 Q6P712 Q32Q15 Q7Z2X1 ENST00000374787.7 [O95347-1] Q5T821 ENST00000440179.5 |