Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 4 studies | 26% ± 6% | |
| glutamatergic neuron | 4 studies | 38% ± 12% | |
| oligodendrocyte | 4 studies | 22% ± 4% | |
| microglial cell | 3 studies | 18% ± 1% | |
| epithelial cell | 3 studies | 17% ± 1% | |
| GABAergic neuron | 3 studies | 41% ± 5% | |
| oligodendrocyte precursor cell | 3 studies | 23% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 31% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1053.70 | 1445 / 1445 | 100% | 14.05 | 183 / 183 |
| ovary | 100% | 1513.23 | 180 / 180 | 100% | 17.48 | 430 / 430 |
| prostate | 100% | 1124.65 | 245 / 245 | 100% | 19.30 | 502 / 502 |
| stomach | 100% | 830.96 | 359 / 359 | 100% | 14.92 | 286 / 286 |
| thymus | 100% | 1233.34 | 653 / 653 | 100% | 19.01 | 605 / 605 |
| skin | 100% | 1534.54 | 1808 / 1809 | 100% | 24.36 | 472 / 472 |
| uterus | 100% | 1432.37 | 170 / 170 | 100% | 18.27 | 458 / 459 |
| breast | 100% | 1299.30 | 459 / 459 | 100% | 23.18 | 1115 / 1118 |
| intestine | 100% | 1108.31 | 966 / 966 | 100% | 15.90 | 525 / 527 |
| bladder | 100% | 1215.81 | 21 / 21 | 100% | 16.20 | 502 / 504 |
| brain | 100% | 736.28 | 2630 / 2642 | 100% | 15.72 | 705 / 705 |
| pancreas | 99% | 611.34 | 326 / 328 | 100% | 16.99 | 178 / 178 |
| kidney | 100% | 899.21 | 89 / 89 | 99% | 15.83 | 893 / 901 |
| lung | 99% | 961.04 | 572 / 578 | 100% | 16.95 | 1154 / 1155 |
| adrenal gland | 100% | 1313.54 | 257 / 258 | 99% | 13.77 | 227 / 230 |
| liver | 98% | 440.66 | 221 / 226 | 100% | 10.64 | 404 / 406 |
| adipose | 100% | 1273.74 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 20.12 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 27.47 | 29 / 29 |
| spleen | 100% | 1305.77 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 18.17 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 11.18 | 1 / 1 |
| blood vessel | 100% | 1187.89 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 781.19 | 795 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 723.68 | 845 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 1002.76 | 909 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006974 | Biological process | DNA damage response |
| GO_0090656 | Biological process | t-circle formation |
| GO_0031297 | Biological process | replication fork processing |
| GO_0006303 | Biological process | double-strand break repair via nonhomologous end joining |
| GO_0006281 | Biological process | DNA repair |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0043596 | Cellular component | nuclear replication fork |
| GO_0005662 | Cellular component | DNA replication factor A complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0035861 | Cellular component | site of double-strand break |
| GO_0005634 | Cellular component | nucleus |
| GO_0140658 | Molecular function | ATP-dependent chromatin remodeler activity |
| GO_0004386 | Molecular function | helicase activity |
| GO_0016787 | Molecular function | hydrolase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0036310 | Molecular function | ATP-dependent DNA/DNA annealing activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | SMARCAL1 |
| Protein name | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (HepA-related protein) (Sucrose nonfermenting protein 2-like 1) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (hHARP) (Sucrose nonfermenting protein 2-like 1) SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 |
| Synonyms | HARP |
| Description | FUNCTION: ATP-dependent annealing helicase that binds selectively to fork DNA relative to ssDNA or dsDNA and catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the genome to reanneal stably unwound DNA, performing the opposite reaction of many enzymes, such as helicases and polymerases, that unwind DNA. May play an important role in DNA damage response by acting at stalled replication forks. . |
| Accessions | ENST00000697907.1 ENST00000697904.1 C9J8F8 A0A8V8TMS6 H7C1I3 ENST00000434435.1 ENST00000425815.5 ENST00000697905.1 ENST00000392128.6 ENST00000697903.1 Q9NZC9 ENST00000430374.6 C9JHQ1 ENST00000412913.1 ENST00000430374.5 A0A8V8TLD4 ENST00000697899.1 ENST00000357276.9 ENST00000697901.1 ENST00000427645.5 ENST00000444508.5 ENST00000425815.6 A0A8V8TLB3 C9JS37 H7BYI2 ENST00000358207.9 C9J6I8 H7C051 ENST00000444508.6 ENST00000697906.1 ENST00000445153.1 C9JP32 |
