SLC6A6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0050804Biological processmodulation of chemical synaptic transmission
GO_0150104Biological processtransport across blood-brain barrier
GO_0098739Biological processimport across plasma membrane
GO_0015734Biological processtaurine transmembrane transport
GO_0032328Biological processalanine transport
GO_0045597Biological processpositive regulation of cell differentiation
GO_0089718Biological processamino acid import across plasma membrane
GO_0006836Biological processneurotransmitter transport
GO_0006865Biological processamino acid transport
GO_0071705Biological processnitrogen compound transport
GO_0051939Biological processgamma-aminobutyric acid import
GO_0035725Biological processsodium ion transmembrane transport
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0031528Cellular componentmicrovillus membrane
GO_0043025Cellular componentneuronal cell body
GO_0030425Cellular componentdendrite
GO_0098982Cellular componentGABA-ergic synapse
GO_0098797Cellular componentplasma membrane protein complex
GO_0045211Cellular componentpostsynaptic membrane
GO_0042995Cellular componentcell projection
GO_0016323Cellular componentbasolateral plasma membrane
GO_0005283Molecular functionamino acid:sodium symporter activity
GO_0015171Molecular functionamino acid transmembrane transporter activity
GO_0005368Molecular functiontaurine transmembrane transporter activity
GO_0022858Molecular functionalanine transmembrane transporter activity
GO_0005332Molecular functiongamma-aminobutyric acid:sodium:chloride symporter activity
GO_0015185Molecular functiongamma-aminobutyric acid transmembrane transporter activity
GO_0005369Molecular functiontaurine:sodium symporter activity

IV. Literature review

[source]
Gene nameSLC6A6
Protein nameSolute carrier family 6 member 6
Transporter
Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6)
Synonyms
DescriptionFUNCTION: Mediates sodium- and chloride-dependent transport of taurine . Mediates transport of beta-alanine . Can also mediate transport of hypotaurine and gamma-aminobutyric acid (GABA) (By similarity). .; FUNCTION: Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. .

AccessionsENST00000622176.4
ENST00000613060.4
A0A087WYN0
H7C1B9
ENST00000618278.4
ENST00000452151.1
A0A087WYY8
ENST00000622186.5 [P31641-1]
C9JPV1
ENST00000649500.1
A0A087WZ59
A0A087WY96
P31641
ENST00000610642.4
ENST00000452775.1
ENST00000621751.4 [P31641-2]