Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 12 studies | 25% ± 10% | |
| macrophage | 12 studies | 22% ± 6% | |
| ciliated cell | 10 studies | 27% ± 13% | |
| basal cell | 9 studies | 29% ± 9% | |
| non-classical monocyte | 9 studies | 27% ± 13% | |
| retinal cone cell | 9 studies | 61% ± 23% | |
| retinal rod cell | 8 studies | 55% ± 19% | |
| monocyte | 7 studies | 22% ± 6% | |
| endothelial cell | 7 studies | 35% ± 15% | |
| dendritic cell | 7 studies | 25% ± 9% | |
| myeloid cell | 5 studies | 32% ± 14% | |
| epithelial cell | 4 studies | 34% ± 14% | |
| neutrophil | 4 studies | 22% ± 4% | |
| conventional dendritic cell | 4 studies | 19% ± 1% | |
| retinal bipolar neuron | 4 studies | 26% ± 1% | |
| microglial cell | 4 studies | 28% ± 12% | |
| alveolar macrophage | 4 studies | 32% ± 14% | |
| secretory cell | 3 studies | 27% ± 5% | |
| capillary endothelial cell | 3 studies | 30% ± 5% | |
| amacrine cell | 3 studies | 42% ± 27% | |
| retinal pigment epithelial cell | 3 studies | 31% ± 8% | |
| fibroblast | 3 studies | 33% ± 9% | |
| rod bipolar cell | 3 studies | 25% ± 8% | |
| GABAergic neuron | 3 studies | 35% ± 7% | |
| glutamatergic neuron | 3 studies | 35% ± 10% | |
| oligodendrocyte | 3 studies | 22% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 9080.04 | 578 / 578 | 99% | 38.69 | 1148 / 1155 |
| bladder | 100% | 2910.05 | 21 / 21 | 94% | 34.49 | 474 / 504 |
| breast | 97% | 3840.22 | 447 / 459 | 95% | 26.99 | 1061 / 1118 |
| kidney | 100% | 5941.64 | 89 / 89 | 89% | 27.79 | 802 / 901 |
| thymus | 100% | 4698.63 | 650 / 653 | 89% | 26.39 | 540 / 605 |
| stomach | 88% | 2577.03 | 316 / 359 | 99% | 44.62 | 284 / 286 |
| esophagus | 88% | 2212.50 | 1267 / 1445 | 98% | 31.55 | 179 / 183 |
| ovary | 99% | 16385.20 | 179 / 180 | 83% | 15.94 | 355 / 430 |
| uterus | 98% | 5233.84 | 167 / 170 | 83% | 17.94 | 380 / 459 |
| intestine | 82% | 2824.79 | 789 / 966 | 99% | 46.65 | 521 / 527 |
| skin | 91% | 5869.22 | 1647 / 1809 | 87% | 20.22 | 411 / 472 |
| adrenal gland | 100% | 10495.53 | 258 / 258 | 57% | 11.19 | 132 / 230 |
| brain | 80% | 2148.78 | 2123 / 2642 | 53% | 6.77 | 373 / 705 |
| prostate | 89% | 2736.78 | 217 / 245 | 43% | 4.16 | 215 / 502 |
| pancreas | 19% | 299.91 | 61 / 328 | 97% | 48.84 | 172 / 178 |
| spleen | 100% | 10471.77 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 17.48 | 1 / 1 |
| peripheral blood | 99% | 20365.22 | 924 / 929 | 0% | 0 | 0 / 0 |
| adipose | 98% | 4229.20 | 1179 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 97% | 6941.10 | 781 / 803 | 0% | 0 | 0 / 0 |
| heart | 92% | 5735.61 | 796 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 28.74 | 41 / 45 |
| blood vessel | 83% | 2373.93 | 1112 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 16.53 | 21 / 29 |
| eye | 0% | 0 | 0 / 0 | 66% | 11.51 | 53 / 80 |
| liver | 5% | 84.37 | 12 / 226 | 23% | 5.03 | 92 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0050804 | Biological process | modulation of chemical synaptic transmission |
| GO_0150104 | Biological process | transport across blood-brain barrier |
| GO_0098739 | Biological process | import across plasma membrane |
| GO_0015734 | Biological process | taurine transmembrane transport |
| GO_0032328 | Biological process | alanine transport |
| GO_0045597 | Biological process | positive regulation of cell differentiation |
| GO_0089718 | Biological process | amino acid import across plasma membrane |
| GO_0006836 | Biological process | neurotransmitter transport |
| GO_0006865 | Biological process | amino acid transport |
| GO_0071705 | Biological process | nitrogen compound transport |
| GO_0051939 | Biological process | gamma-aminobutyric acid import |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0031528 | Cellular component | microvillus membrane |
| GO_0043025 | Cellular component | neuronal cell body |
| GO_0030425 | Cellular component | dendrite |
| GO_0098982 | Cellular component | GABA-ergic synapse |
| GO_0098797 | Cellular component | plasma membrane protein complex |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0042995 | Cellular component | cell projection |
| GO_0016323 | Cellular component | basolateral plasma membrane |
| GO_0005283 | Molecular function | amino acid:sodium symporter activity |
| GO_0015171 | Molecular function | amino acid transmembrane transporter activity |
| GO_0005368 | Molecular function | taurine transmembrane transporter activity |
| GO_0022858 | Molecular function | alanine transmembrane transporter activity |
| GO_0005332 | Molecular function | gamma-aminobutyric acid:sodium:chloride symporter activity |
| GO_0015185 | Molecular function | gamma-aminobutyric acid transmembrane transporter activity |
| GO_0005369 | Molecular function | taurine:sodium symporter activity |
| Gene name | SLC6A6 |
| Protein name | Solute carrier family 6 member 6 Transporter Sodium- and chloride-dependent taurine transporter (Solute carrier family 6 member 6) |
| Synonyms | |
| Description | FUNCTION: Mediates sodium- and chloride-dependent transport of taurine . Mediates transport of beta-alanine . Can also mediate transport of hypotaurine and gamma-aminobutyric acid (GABA) (By similarity). .; FUNCTION: Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake. . |
| Accessions | ENST00000622176.4 ENST00000613060.4 A0A087WYN0 H7C1B9 ENST00000618278.4 ENST00000452151.1 A0A087WYY8 ENST00000622186.5 [P31641-1] C9JPV1 ENST00000649500.1 A0A087WZ59 A0A087WY96 P31641 ENST00000610642.4 ENST00000452775.1 ENST00000621751.4 [P31641-2] |