SLC6A12 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	3 studies	37% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC6A12 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	100%	5262.84	89 / 89	97%	34.50	874 / 901
brain	100%	2011.30	2639 / 2642	86%	5.44	609 / 705
liver	100%	2948.22	225 / 226	85%	22.31	344 / 406
thymus	99%	1265.17	646 / 653	81%	10.67	493 / 605
ureter	0%	0	0 / 0	100%	2.41	1 / 1
ovary	16%	42.96	28 / 180	83%	8.88	356 / 430
lung	40%	127.29	234 / 578	21%	0.83	237 / 1155
pancreas	38%	171.83	123 / 328	22%	0.86	39 / 178
uterus	37%	192.79	63 / 170	20%	1.20	90 / 459
lymph node	0%	0	0 / 0	45%	2.05	13 / 29
skin	1%	1.56	13 / 1809	32%	1.61	149 / 472
peripheral blood	29%	154.36	274 / 929	0%	0	0 / 0
breast	6%	18.95	27 / 459	13%	0.80	146 / 1118
stomach	1%	2.79	5 / 359	15%	0.64	43 / 286
eye	0%	0	0 / 0	16%	0.40	13 / 80
intestine	4%	9.63	38 / 966	10%	0.41	53 / 527
bladder	0%	0	0 / 21	12%	0.56	58 / 504
adrenal gland	7%	40.33	18 / 258	3%	0.11	7 / 230
spleen	10%	32.18	24 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	9%	0.23	4 / 45
esophagus	0%	0.67	5 / 1445	6%	0.20	11 / 183
adipose	3%	10.42	39 / 1204	0%	0	0 / 0
blood vessel	2%	4.32	22 / 1335	0%	0	0 / 0
heart	1%	2.56	10 / 861	0%	0	0 / 0
muscle	0%	1.00	3 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
prostate	0%	0	0 / 245	0%	0	0 / 502
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006865	Biological process	amino acid transport
GO_0015718	Biological process	monocarboxylic acid transport
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0031460	Biological process	glycine betaine transport
GO_0003333	Biological process	amino acid transmembrane transport
GO_0051936	Biological process	gamma-aminobutyric acid reuptake
GO_0015812	Biological process	gamma-aminobutyric acid transport
GO_0016323	Cellular component	basolateral plasma membrane
GO_0042995	Cellular component	cell projection
GO_0098793	Cellular component	presynapse
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0015171	Molecular function	amino acid transmembrane transporter activity
GO_0008028	Molecular function	monocarboxylic acid transmembrane transporter activity
GO_0005515	Molecular function	protein binding
GO_0005332	Molecular function	gamma-aminobutyric acid:sodium:chloride symporter activity

Gene name	SLC6A12
Protein name	Transporter Sodium- and chloride-dependent betaine transporter (BGT-1) (Na(+)/Cl(-) betaine/GABA transporter) (Solute carrier family 6 member 12) Solute carrier family 6 member 12
Synonyms	BGT1
Description	FUNCTION: Transporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process . May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. Probably also involved in renal and hepatic osmotic regulation (By similarity). .
Accessions	ENST00000684302.1 ENST00000535347.5 ENST00000537793.1 F5H4L6 ENST00000424061.6 P48065 ENST00000536824.5 F5H2T6 ENST00000397296.6 ENST00000359674.8

SLC6A12 report