I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 13 studies | 47% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 13 studies | 47% ± 17% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 26% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 98% | 1379.34 | 2592 / 2642 | 78% | 8.26 | 553 / 705 |
| kidney | 94% | 216.15 | 84 / 89 | 15% | 0.63 | 138 / 901 |
| liver | 54% | 39.31 | 121 / 226 | 36% | 1.97 | 148 / 406 |
| intestine | 32% | 176.73 | 312 / 966 | 6% | 0.11 | 30 / 527 |
| spleen | 36% | 26.29 | 86 / 241 | 0% | 0 | 0 / 0 |
| lung | 24% | 13.56 | 136 / 578 | 10% | 0.36 | 110 / 1155 |
| breast | 19% | 10.60 | 85 / 459 | 11% | 0.33 | 127 / 1118 |
| prostate | 23% | 14.72 | 57 / 245 | 2% | 0.04 | 11 / 502 |
| pancreas | 21% | 12.20 | 69 / 328 | 2% | 0.04 | 4 / 178 |
| thymus | 22% | 11.72 | 143 / 653 | 0% | 0.00 | 2 / 605 |
| bladder | 14% | 6.95 | 3 / 21 | 4% | 0.31 | 22 / 504 |
| adipose | 17% | 8.79 | 205 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 11% | 5.99 | 19 / 170 | 4% | 0.09 | 20 / 459 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.29 | 4 / 29 |
| ovary | 12% | 6.28 | 21 / 180 | 1% | 0.02 | 6 / 430 |
| stomach | 4% | 1.85 | 16 / 359 | 8% | 0.14 | 24 / 286 |
| blood vessel | 13% | 6.05 | 167 / 1335 | 0% | 0 | 0 / 0 |
| esophagus | 4% | 1.94 | 61 / 1445 | 8% | 0.25 | 14 / 183 |
| skin | 10% | 4.75 | 179 / 1809 | 0% | 0.00 | 2 / 472 |
| adrenal gland | 9% | 4.21 | 22 / 258 | 1% | 0.01 | 2 / 230 |
| peripheral blood | 7% | 3.65 | 68 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 0.05 | 2 / 45 |
| heart | 2% | 0.83 | 13 / 861 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.49 | 10 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006915 | Biological process | apoptotic process |
| GO_0015791 | Biological process | polyol transmembrane transport |
| GO_0015798 | Biological process | myo-inositol transport |
| GO_1904659 | Biological process | glucose transmembrane transport |
| GO_0006814 | Biological process | sodium ion transport |
| GO_0016324 | Cellular component | apical plasma membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005365 | Molecular function | myo-inositol transmembrane transporter activity |
| GO_0005412 | Molecular function | glucose:sodium symporter activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0015166 | Molecular function | polyol transmembrane transporter activity |
| Gene name | SLC5A11 |
| Protein name | Sodium/myo-inositol cotransporter 2 (Sodium/myo-inositol transporter 2) (Solute carrier family 5 member 11) Sodium/myo-inositol cotransporter 2 (Na(+)/myo-inositol cotransporter 2) (Sodium-dependent glucose cotransporter) (Sodium/glucose cotransporter KST1) (Sodium/myo-inositol transporter 2) (SMIT2) (Solute carrier family 5 member 11) Solute carrier family 5 member 11 |
| Synonyms | SLGTX SMIT2 KST1 |
| Description | FUNCTION: Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1 . Exclusively responsible for apical MI transport and absorption in intestine (By similarity). Can also transport D-chiro-inositol (DCI) but not L-fucose . Exhibits stereospecific cotransport of both D-glucose and D-xylose (By similarity). May induce apoptosis through the TNF-alpha, PDCD1 pathway . May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney (By similarity). . |
| Accessions | ENST00000424767.7 [Q8WWX8-1] ENST00000672547.1 [Q8WWX8-2] ENST00000671711.1 [Q8WWX8-6] ENST00000710486.1 [Q8WWX8-1] ENST00000568579.6 [Q8WWX8-5] ENST00000545376.6 ENST00000488922.6 ENST00000673441.1 [Q8WWX8-3] ENST00000672306.1 [Q8WWX8-6] Q8WWX8 H3BN85 ENST00000347898.7 [Q8WWX8-1] ENST00000569520.5 ENST00000672588.1 [Q8WWX8-1] ENST00000569071.2 [Q8WWX8-6] ENST00000565769.5 [Q8WWX8-3] A0A8J9ASH1 ENST00000567758.6 [Q8WWX8-2] ENST00000673269.1 [Q8WWX8-2] ENST00000672971.1 [Q8WWX8-5] ENST00000672672.1 [Q8WWX8-5] I3L1G0 |
