SLC35B1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015866Biological processADP transport
GO_0015786Biological processUDP-glucose transmembrane transport
GO_0072334Biological processUDP-galactose transmembrane transport
GO_0015867Biological processATP transport
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0000139Cellular componentGolgi membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005459Molecular functionUDP-galactose transmembrane transporter activity
GO_0005471Molecular functionATP:ADP antiporter activity
GO_0005460Molecular functionUDP-glucose transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC35B1
Protein nameSolute carrier family 35 member B1
Solute carrier family 35 member B1 (ATP/ADP exchanger ER) (AXER) (Endoplasmic reticulum ATP/ADP translocase) (UDP-galactose transporter-related protein 1) (UGTrel1)
SynonymsUGTREL1
DescriptionFUNCTION: ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane. Imports ATP from the cytosol to the ER lumen and exports ADP in the opposite direction . Regulates ER energy metabolism and protein biogenesis. Appears to be part of a calcium-dependent ER to cytosol low energy response axis, where calcium efflux from ER to the cytosol triggers ATP import into the ER lumen to maintain sufficient ATP supply. Provides ATP to ER chaperone HSPA5 that drives protein folding and trafficking in the ER . Can transport dATP, UTP or UDP in exchange for ATP, but the physiological relevance of this process remains to be established . .; FUNCTION: [Isoform 1]: ATP:ADP antiporter. .; FUNCTION: [Isoform 2]: ATP:ADP antiporter. .

AccessionsENST00000511763.6
P78383
ENST00000507773.6
D6RE58
D6RF81
ENST00000503334.5
ENST00000649906.1 [P78383-2]
ENST00000502268.5
D6RB73
D6RG34
ENST00000514907.5
ENST00000508520.5
D6R981
ENST00000240333.12 [P78383-1]
ENST00000511657.1
ENST00000515850.6
D6RDY9
D6R9G9
D6RHG0