SLC30A8 | OmnibusX

Name	Number of supported studies	Average coverage
pancreas	3 studies	56% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	1818.25	328 / 328	74%	45.81	131 / 178
stomach	81%	96.62	290 / 359	3%	0.15	8 / 286
kidney	74%	86.51	66 / 89	7%	0.28	64 / 901
intestine	74%	42.38	716 / 966	3%	2.45	18 / 527
bladder	71%	69.81	15 / 21	4%	0.11	18 / 504
uterus	69%	61.64	117 / 170	2%	0.06	10 / 459
breast	27%	26.29	125 / 459	39%	38.84	431 / 1118
thymus	54%	26.22	352 / 653	10%	0.41	63 / 605
esophagus	56%	34.32	810 / 1445	4%	0.35	7 / 183
skin	23%	14.24	415 / 1809	13%	1.02	61 / 472
lung	28%	15.54	164 / 578	7%	0.44	81 / 1155
prostate	30%	20.60	73 / 245	1%	0.06	7 / 502
brain	29%	11.06	760 / 2642	0%	0.00	2 / 705
adrenal gland	21%	9.85	53 / 258	0%	0	0 / 230
spleen	17%	3.98	42 / 241	0%	0	0 / 0
blood vessel	14%	6.59	185 / 1335	0%	0	0 / 0
ovary	12%	2.53	21 / 180	1%	0.02	4 / 430
lymph node	0%	0	0 / 0	7%	0.21	2 / 29
peripheral blood	4%	1.97	33 / 929	0%	0	0 / 0
heart	3%	0.68	29 / 861	0%	0	0 / 0
liver	0%	0.06	1 / 226	2%	0.20	9 / 406
adipose	2%	1.10	30 / 1204	0%	0	0 / 0
muscle	0%	0.06	4 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0071577	Biological process	zinc ion transmembrane transport
GO_0009749	Biological process	response to glucose
GO_0062111	Biological process	zinc ion import into organelle
GO_0060627	Biological process	regulation of vesicle-mediated transport
GO_0070555	Biological process	response to interleukin-1
GO_0034341	Biological process	response to type II interferon
GO_0032024	Biological process	positive regulation of insulin secretion
GO_0006882	Biological process	intracellular zinc ion homeostasis
GO_0010043	Biological process	response to zinc ion
GO_0006829	Biological process	zinc ion transport
GO_0030073	Biological process	insulin secretion
GO_0071578	Biological process	zinc ion import across plasma membrane
GO_0030070	Biological process	insulin processing
GO_0042593	Biological process	glucose homeostasis
GO_0030667	Cellular component	secretory granule membrane
GO_0005886	Cellular component	plasma membrane
GO_0031410	Cellular component	cytoplasmic vesicle
GO_0005794	Cellular component	Golgi apparatus
GO_0000139	Cellular component	Golgi membrane
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0030141	Cellular component	secretory granule
GO_0030658	Cellular component	transport vesicle membrane
GO_0042803	Molecular function	protein homodimerization activity
GO_0005385	Molecular function	zinc ion transmembrane transporter activity
GO_0140826	Molecular function	zinc:proton antiporter activity
GO_0008270	Molecular function	zinc ion binding
GO_0005515	Molecular function	protein binding

Gene name	SLC30A8
Protein name	Proton-coupled zinc antiporter SLC30A8 (Solute carrier family 30 member 8) (Zinc transporter 8) (ZnT-8) Solute carrier family 30 member 8 Proton-coupled zinc antiporter SLC30A8 (Solute carrier family 30 member 8) (Zinc transporter 8)
Synonyms	ZNT8
Description	FUNCTION: Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion. . FUNCTION: Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion. .
Accessions	ENST00000519688.5 [Q8IWU4-2] A0A096LPF3 ENST00000521243.5 [Q8IWU4-2] ENST00000456015.7 [Q8IWU4-1] ENST00000427715.2 [Q8IWU4-2] ENST00000518521.5 ENST00000524274.5 Q8IWU4 ENST00000518396.5 E5RG87 A0A096LNR0

SLC30A8 report