Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 8 studies | 19% ± 3% | |
epithelial cell | 6 studies | 31% ± 11% | |
plasmacytoid dendritic cell | 5 studies | 24% ± 6% | |
ciliated cell | 4 studies | 27% ± 10% | |
astrocyte | 4 studies | 21% ± 4% | |
glutamatergic neuron | 4 studies | 40% ± 17% | |
oligodendrocyte | 4 studies | 18% ± 2% | |
fibroblast | 3 studies | 20% ± 4% | |
GABAergic neuron | 3 studies | 39% ± 7% | |
oligodendrocyte precursor cell | 3 studies | 22% ± 4% | |
dendritic cell | 3 studies | 23% ± 8% | |
macrophage | 3 studies | 17% ± 1% | |
basal cell | 3 studies | 28% ± 4% | |
goblet cell | 3 studies | 30% ± 11% | |
neuron | 3 studies | 23% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1721.19 | 1445 / 1445 | 100% | 25.74 | 183 / 183 |
lung | 100% | 2154.40 | 578 / 578 | 100% | 26.92 | 1155 / 1155 |
ovary | 100% | 2297.94 | 180 / 180 | 100% | 20.83 | 430 / 430 |
stomach | 100% | 1717.97 | 359 / 359 | 100% | 26.00 | 286 / 286 |
breast | 100% | 2283.29 | 459 / 459 | 100% | 36.65 | 1117 / 1118 |
intestine | 100% | 1976.24 | 966 / 966 | 100% | 25.97 | 526 / 527 |
uterus | 100% | 2586.04 | 170 / 170 | 100% | 24.34 | 458 / 459 |
prostate | 100% | 2152.84 | 245 / 245 | 100% | 33.59 | 500 / 502 |
bladder | 100% | 1967.52 | 21 / 21 | 99% | 23.05 | 501 / 504 |
thymus | 100% | 2740.24 | 653 / 653 | 99% | 30.62 | 601 / 605 |
kidney | 100% | 1580.99 | 89 / 89 | 99% | 21.83 | 892 / 901 |
pancreas | 100% | 1859.38 | 328 / 328 | 99% | 22.08 | 176 / 178 |
adrenal gland | 100% | 2116.34 | 258 / 258 | 99% | 20.37 | 227 / 230 |
brain | 99% | 986.99 | 2603 / 2642 | 100% | 17.34 | 705 / 705 |
liver | 100% | 1456.55 | 226 / 226 | 98% | 15.22 | 397 / 406 |
skin | 100% | 2486.08 | 1809 / 1809 | 96% | 27.12 | 453 / 472 |
adipose | 100% | 2147.30 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 17.47 | 29 / 29 |
spleen | 100% | 1704.75 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 21.90 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 8.38 | 1 / 1 |
blood vessel | 100% | 1854.88 | 1334 / 1335 | 0% | 0 | 0 / 0 |
muscle | 99% | 819.68 | 795 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 1480.42 | 851 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 12.86 | 72 / 80 |
peripheral blood | 65% | 913.00 | 606 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0071577 | Biological process | zinc ion transmembrane transport |
GO_0062111 | Biological process | zinc ion import into organelle |
GO_0006506 | Biological process | GPI anchor biosynthetic process |
GO_1904257 | Biological process | zinc ion import into Golgi lumen |
GO_0006882 | Biological process | intracellular zinc ion homeostasis |
GO_0006829 | Biological process | zinc ion transport |
GO_0030070 | Biological process | insulin processing |
GO_0006824 | Biological process | cobalt ion transport |
GO_0016324 | Cellular component | apical plasma membrane |
GO_1990674 | Cellular component | Golgi cis cisterna membrane |
GO_0005730 | Cellular component | nucleolus |
GO_0030667 | Cellular component | secretory granule membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0016020 | Cellular component | membrane |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0000139 | Cellular component | Golgi membrane |
GO_0012507 | Cellular component | ER to Golgi transport vesicle membrane |
GO_0030141 | Cellular component | secretory granule |
GO_0005385 | Molecular function | zinc ion transmembrane transporter activity |
GO_0015297 | Molecular function | antiporter activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SLC30A5 |
Protein name | Zinc transporter Solute carrier family 30 member 5 Proton-coupled zinc antiporter SLC30A5 (Solute carrier family 30 member 5) (Zinc transporter 5) (ZnT-5) (ZnT-like transporter 1) (hZTL1) |
Synonyms | ZTL1 ZNTL1 UNQ863/PRO1879 ZNT5 |
Description | FUNCTION: Together with SLC30A6 forms a functional proton-coupled zinc ion antiporter mediating zinc entry into the lumen of organelles along the secretory pathway . By contributing to zinc ion homeostasis within the early secretory pathway, regulates the activation and folding of enzymes like alkaline phosphatases and enzymes involved in phosphatidylinositol glycan anchor biosynthesis . Through the transport of zinc into secretory granules of pancreatic beta-cells, plays an important role in the storage and secretion of insulin . .; FUNCTION: [Isoform 2]: Zinc ion:proton antiporter mediating influx and efflux of zinc at the plasma membrane. . FUNCTION: Functions as a zinc transporter. . |
Accessions | H0YAH4 Q8TAD4 ENST00000513937.1 ENST00000396591.8 [Q8TAD4-1] ENST00000502979.1 [Q8TAD4-4] ENST00000504103.5 H0Y957 D6REM2 ENST00000380860.8 [Q8TAD4-3] ENST00000511158.1 |