Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 3 studies | 21% ± 5% | |
| plasmacytoid dendritic cell | 3 studies | 17% ± 3% |
Insufficient scRNA-seq data for expression of SLC2A8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 1766.70 | 226 / 226 | 100% | 21.58 | 406 / 406 |
| brain | 100% | 1563.51 | 2639 / 2642 | 100% | 22.21 | 705 / 705 |
| stomach | 100% | 1777.41 | 358 / 359 | 100% | 28.70 | 286 / 286 |
| kidney | 100% | 1216.42 | 89 / 89 | 100% | 16.96 | 897 / 901 |
| esophagus | 100% | 1218.82 | 1445 / 1445 | 99% | 14.29 | 182 / 183 |
| prostate | 100% | 1725.20 | 245 / 245 | 99% | 21.94 | 499 / 502 |
| ovary | 100% | 1168.43 | 180 / 180 | 99% | 14.26 | 427 / 430 |
| intestine | 100% | 2462.30 | 966 / 966 | 99% | 34.25 | 523 / 527 |
| adrenal gland | 100% | 3776.31 | 258 / 258 | 99% | 24.31 | 228 / 230 |
| uterus | 100% | 1569.21 | 170 / 170 | 99% | 20.88 | 455 / 459 |
| bladder | 100% | 5408.57 | 21 / 21 | 99% | 29.32 | 499 / 504 |
| thymus | 100% | 1552.23 | 653 / 653 | 99% | 13.51 | 597 / 605 |
| breast | 100% | 1199.87 | 459 / 459 | 99% | 17.67 | 1102 / 1118 |
| pancreas | 99% | 625.15 | 325 / 328 | 99% | 14.00 | 177 / 178 |
| lung | 99% | 1101.00 | 575 / 578 | 99% | 16.72 | 1143 / 1155 |
| skin | 97% | 948.47 | 1763 / 1809 | 94% | 14.93 | 442 / 472 |
| adipose | 100% | 1289.03 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 17.62 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 19.33 | 29 / 29 |
| muscle | 100% | 1398.19 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1530.37 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 19.57 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.28 | 1 / 1 |
| blood vessel | 100% | 1211.05 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 874.70 | 848 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 44% | 236.43 | 410 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0005975 | Biological process | carbohydrate metabolic process |
| GO_0008645 | Biological process | hexose transmembrane transport |
| GO_0008286 | Biological process | insulin receptor signaling pathway |
| GO_1904659 | Biological process | glucose transmembrane transport |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0015755 | Biological process | fructose transmembrane transport |
| GO_0070837 | Biological process | dehydroascorbic acid transport |
| GO_0030669 | Cellular component | clathrin-coated endocytic vesicle membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0033300 | Molecular function | dehydroascorbic acid transmembrane transporter activity |
| GO_0005353 | Molecular function | fructose transmembrane transporter activity |
| GO_0055056 | Molecular function | D-glucose transmembrane transporter activity |
| GO_0005536 | Molecular function | D-glucose binding |
| GO_0005355 | Molecular function | glucose transmembrane transporter activity |
| Gene name | SLC2A8 |
| Protein name | Solute carrier family 2 member 8 (Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_c) Solute carrier family 2 member 8 Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) Solute carrier family 2 member 8 (Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_b) Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_d |
| Synonyms | GLUT8 hCG_28276 GLUTX1 |
| Description | FUNCTION: Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose (By similarity). Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1 . Also able to mediate the transport of dehydroascorbate. . |
| Accessions | ENST00000373360.7 Q8WZ05 ENST00000423934.5 ENST00000610552.4 Q5VVV5 Q5VVV9 ENST00000373352.5 Q5VVV4 ENST00000451404.5 ENST00000373371.8 Q5VVW0 Q5VVV3 Q9NY64 ENST00000419132.5 H0Y7M6 A0A087WT42 ENST00000430147.1 Q5VVV6 Q5VVW5 ENST00000439597.5 ENST00000419917.5 |