SLC2A8 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC2A8 at tissue level.

III. Associated gene sets

GO_0005975Biological processcarbohydrate metabolic process
GO_0008645Biological processhexose transmembrane transport
GO_0008286Biological processinsulin receptor signaling pathway
GO_1904659Biological processglucose transmembrane transport
GO_0001666Biological processresponse to hypoxia
GO_0015755Biological processfructose transmembrane transport
GO_0070837Biological processdehydroascorbic acid transport
GO_0030669Cellular componentclathrin-coated endocytic vesicle membrane
GO_0005886Cellular componentplasma membrane
GO_0005765Cellular componentlysosomal membrane
GO_0016020Cellular componentmembrane
GO_0033300Molecular functiondehydroascorbic acid transmembrane transporter activity
GO_0005353Molecular functionfructose transmembrane transporter activity
GO_0055056Molecular functionD-glucose transmembrane transporter activity
GO_0005536Molecular functionD-glucose binding
GO_0005355Molecular functionglucose transmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC2A8
Protein nameSolute carrier family 2 member 8 (Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_c)
Solute carrier family 2 member 8
Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1)
Solute carrier family 2 member 8 (Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_b)
Solute carrier family 2, (Facilitated glucose transporter) member 8, isoform CRA_d
SynonymsGLUT8
hCG_28276
GLUTX1
DescriptionFUNCTION: Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose (By similarity). Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1 . Also able to mediate the transport of dehydroascorbate. .

AccessionsENST00000373360.7
Q8WZ05
ENST00000423934.5
ENST00000610552.4
Q5VVV5
Q5VVV9
ENST00000373352.5
Q5VVV4
ENST00000451404.5
ENST00000373371.8
Q5VVW0
Q5VVV3
Q9NY64
ENST00000419132.5
H0Y7M6
A0A087WT42
ENST00000430147.1
Q5VVV6
Q5VVW5
ENST00000439597.5
ENST00000419917.5