SLC2A4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC2A4 at tissue level.

III. Associated gene sets

GO_0050873Biological processbrown fat cell differentiation
GO_1904659Biological processglucose transmembrane transport
GO_0032869Biological processcellular response to insulin stimulus
GO_0098694Biological processregulation of synaptic vesicle budding from presynaptic endocytic zone membrane
GO_0007611Biological processlearning or memory
GO_0007616Biological processlong-term memory
GO_0150104Biological processtransport across blood-brain barrier
GO_0005975Biological processcarbohydrate metabolic process
GO_0045471Biological processresponse to ethanol
GO_0070343Biological processwhite fat cell proliferation
GO_0044381Biological processglucose import in response to insulin stimulus
GO_0070837Biological processdehydroascorbic acid transport
GO_0071356Biological processcellular response to tumor necrosis factor
GO_0071470Biological processcellular response to osmotic stress
GO_0010021Biological processamylopectin biosynthetic process
GO_0046323Biological processglucose import
GO_0031550Biological processpositive regulation of brain-derived neurotrophic factor receptor signaling pathway
GO_0007614Biological processshort-term memory
GO_0042593Biological processglucose homeostasis
GO_0071456Biological processcellular response to hypoxia
GO_0098793Cellular componentpresynapse
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0045121Cellular componentmembrane raft
GO_0012506Cellular componentvesicle membrane
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0012505Cellular componentendomembrane system
GO_0016020Cellular componentmembrane
GO_0042383Cellular componentsarcolemma
GO_0070062Cellular componentextracellular exosome
GO_0030136Cellular componentclathrin-coated vesicle
GO_0005802Cellular componenttrans-Golgi network
GO_0030315Cellular componentT-tubule
GO_0005829Cellular componentcytosol
GO_0032593Cellular componentinsulin-responsive compartment
GO_0016529Cellular componentsarcoplasmic reticulum
GO_0030140Cellular componenttrans-Golgi network transport vesicle
GO_0005771Cellular componentmultivesicular body
GO_0005905Cellular componentclathrin-coated pit
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_0015304Molecular functionglucose uniporter activity
GO_0055056Molecular functionD-glucose transmembrane transporter activity
GO_0005355Molecular functionglucose transmembrane transporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC2A4
Protein nameSolute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive) (GLUT-4)
Solute carrier family 2, facilitated glucose transporter member 4 (Glucose transporter type 4, insulin-responsive)
Solute carrier family 2 member 4
SynonymsGLUT4
hCG_42005
DescriptionFUNCTION: Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell. .

AccessionsENST00000672821.1 [P14672-2]
I3L1S2
F5H081
ENST00000570783.5
ENST00000424875.2
ENST00000571308.5
ENST00000673224.1 [P14672-1]
ENST00000317370.13 [P14672-1]
I3L2R4
P14672
ENST00000572485.5 [P14672-2]