SLC25A38 | OmnibusX

Name	Number of supported studies	Average coverage
CD16-negative, CD56-bright natural killer cell, human	7 studies	19% ± 2%	Explore
regulatory T cell	5 studies	19% ± 3%	Explore
effector memory CD8-positive, alpha-beta T cell	4 studies	16% ± 1%	Explore
epithelial cell	4 studies	30% ± 15%	Explore
natural killer cell	4 studies	19% ± 2%	Explore
CD16-positive, CD56-dim natural killer cell, human	3 studies	19% ± 4%	Explore
CD8-positive, alpha-beta T cell	3 studies	16% ± 0%	Explore
gamma-delta T cell	3 studies	24% ± 10%	Explore
mucosal invariant T cell	3 studies	16% ± 1%	Explore

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC25A38 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	3389.26	258 / 258	100%	60.77	230 / 230
esophagus	100%	2018.90	1445 / 1445	100%	29.53	183 / 183
ovary	100%	3424.02	180 / 180	100%	85.35	430 / 430
pancreas	100%	2519.50	328 / 328	100%	41.69	178 / 178
prostate	100%	3109.87	245 / 245	100%	81.74	502 / 502
stomach	100%	2605.18	359 / 359	100%	43.98	286 / 286
thymus	100%	4068.26	653 / 653	100%	98.29	605 / 605
intestine	100%	2617.97	966 / 966	100%	50.74	526 / 527
bladder	100%	2835.71	21 / 21	100%	51.14	502 / 504
breast	100%	2157.61	459 / 459	100%	51.93	1113 / 1118
kidney	100%	2377.76	89 / 89	99%	31.50	896 / 901
lung	99%	2264.96	575 / 578	100%	38.46	1154 / 1155
uterus	100%	2796.46	170 / 170	99%	44.17	456 / 459
liver	100%	2971.50	226 / 226	99%	39.03	403 / 406
brain	99%	1627.24	2621 / 2642	100%	49.51	705 / 705
skin	100%	1799.82	1808 / 1809	88%	34.88	415 / 472
adipose	100%	1917.75	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	73.52	29 / 29
muscle	100%	2713.88	803 / 803	0%	0	0 / 0
spleen	100%	2744.01	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	38.79	45 / 45
ureter	0%	0	0 / 0	100%	41.73	1 / 1
blood vessel	100%	2684.40	1334 / 1335	0%	0	0 / 0
peripheral blood	97%	1720.92	903 / 929	0%	0	0 / 0
heart	96%	1163.56	824 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	88%	33.36	70 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0030218	Biological process	erythrocyte differentiation
GO_0006783	Biological process	heme biosynthetic process
GO_1904983	Biological process	glycine import into mitochondrion
GO_0005743	Cellular component	mitochondrial inner membrane
GO_0005739	Cellular component	mitochondrion
GO_0015187	Molecular function	glycine transmembrane transporter activity

IV. Literature review

[source]

Gene name	SLC25A38
Protein name	Mitochondrial glycine transporter (Appoptosin) (Mitochondrial glycine transporter GlyC) (Solute carrier family 25 member 38) Mitochondrial glycine transporter (Solute carrier family 25 member 38) Solute carrier family 25 member 38
Synonyms
Description	FUNCTION: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the mitochondrial matrix. Required during erythropoiesis. .; FUNCTION: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis. . FUNCTION: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. .; FUNCTION: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis. . FUNCTION: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. .; FUNCTION: Plays a role as pro-apoptotic protein that induces caspase-dependent apoptosis. .
Accessions	ENST00000643672.1 ENST00000431510.1 ENST00000642683.1 A0A2R8YE85 ENST00000645280.1 ENST00000642978.1 ENST00000645630.1 A0A2R8YD83 ENST00000648579.1 C9JT44 A0A2R8Y823 ENST00000650617.1 A0A2R8Y553 A0A2R8Y427 A0A3B3IT77 Q96DW6

SLC25A38 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review