SLC17A9 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC17A9 at tissue level.

III. Associated gene sets

GO_0141013Biological processpurine nucleotide import into lysosome
GO_0015866Biological processADP transport
GO_1905146Biological processlysosomal protein catabolic process
GO_1903790Biological processguanine nucleotide transmembrane transport
GO_1904669Biological processATP export
GO_0015867Biological processATP transport
GO_0030658Cellular componenttransport vesicle membrane
GO_0098594Cellular componentmucin granule
GO_0005765Cellular componentlysosomal membrane
GO_0042584Cellular componentchromaffin granule membrane
GO_0015217Molecular functionADP transmembrane transporter activity
GO_0160042Molecular functionpurine nucleotide uniporter activity
GO_0001409Molecular functionguanine nucleotide transmembrane transporter activity
GO_0005515Molecular functionprotein binding
GO_0005347Molecular functionATP transmembrane transporter activity

IV. Literature review

[source]
Gene nameSLC17A9
Protein nameVoltage-gated purine nucleotide uniporter SLC17A9 (Solute carrier family 17 member 9) (Vesicular nucleotide transporter) (VNUT)
Solute carrier family 17 member 9
SynonymsC20orf59
DescriptionFUNCTION: Voltage-gated ATP nucleotide uniporter that can also transport the purine nucleotides ADP and GTP. Uses the membrane potential as the driving force to control ATP accumulation in lysosomes and secretory vesicles . By controlling ATP storage in lysosomes, regulates ATP-dependent proteins of these organelles . Also indirectly regulates the exocytosis of ATP through its import into lysosomes in astrocytes and secretory vesicles such as adrenal chromaffin granules, mucin granules and synaptic vesicles . .

AccessionsENST00000370351.9 [Q9BYT1-1]
ENST00000370349.7 [Q9BYT1-2]
Q5W197
ENST00000411611.1
Q9BYT1