SLC10A2 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	3 studies	32% ± 7%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SLC10A2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	94%	272.09	84 / 89	50%	15.63	450 / 901
intestine	47%	2622.54	451 / 966	2%	0.47	10 / 527
skin	38%	4.57	690 / 1809	0%	0	0 / 472
peripheral blood	18%	23.92	168 / 929	0%	0	0 / 0
stomach	13%	3.15	48 / 359	2%	0.37	7 / 286
lung	11%	2.76	64 / 578	3%	1.03	32 / 1155
spleen	13%	0.78	32 / 241	0%	0	0 / 0
esophagus	10%	3.02	143 / 1445	3%	0.28	6 / 183
pancreas	10%	0.51	33 / 328	3%	0.17	5 / 178
liver	11%	0.66	25 / 226	0%	0.03	2 / 406
ovary	10%	1.76	18 / 180	0%	0	0 / 430
prostate	10%	0.47	24 / 245	0%	0	0 / 502
muscle	9%	0.46	73 / 803	0%	0	0 / 0
adrenal gland	8%	0.41	21 / 258	0%	0	0 / 230
breast	7%	0.95	32 / 459	0%	0	0 / 1118
uterus	6%	0.84	11 / 170	0%	0.04	2 / 459
thymus	6%	0.30	36 / 653	0%	0	0 / 605
adipose	5%	0.57	57 / 1204	0%	0	0 / 0
blood vessel	5%	0.39	63 / 1335	0%	0	0 / 0
brain	4%	0.25	104 / 2642	0%	0.01	1 / 705
heart	4%	0.21	33 / 861	0%	0	0 / 0
bladder	0%	0	0 / 21	2%	0.44	10 / 504
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0015721	Biological process	bile acid and bile salt transport
GO_0006814	Biological process	sodium ion transport
GO_0055085	Biological process	transmembrane transport
GO_0009617	Biological process	response to bacterium
GO_0005902	Cellular component	microvillus
GO_0016324	Cellular component	apical plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0008508	Molecular function	bile acid:sodium symporter activity
GO_0005515	Molecular function	protein binding

Gene name	SLC10A2
Protein name	Ileal sodium/bile acid cotransporter (Apical sodium-dependent bile acid transporter) (ASBT) (Ileal Na(+)/bile acid cotransporter) (Ileal sodium-dependent bile acid transporter) (IBAT) (ISBT) (Na(+)-dependent ileal bile acid transporter) (Sodium/taurocholate cotransporting polypeptide, ileal) (Solute carrier family 10 member 2)
Synonyms	NTCP2 ISBT ASBT
Description	FUNCTION: Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine . Transports various bile acids, unconjugated or conjugated, such as cholate and taurocholate . Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable). Works collaboratively with the Na(+)-taurocholate cotransporting polypeptide (NTCP), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation . .
Accessions	Q12908 ENST00000245312.5

SLC10A2 report