Insufficient scRNA-seq data for expression of SIGLEC6 at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 97% | 89.41 | 560 / 578 | 42% | 1.22 | 482 / 1155 |
| stomach | 92% | 38.93 | 332 / 359 | 26% | 0.58 | 74 / 286 |
| bladder | 100% | 80.76 | 21 / 21 | 18% | 1.51 | 92 / 504 |
| prostate | 89% | 42.81 | 218 / 245 | 24% | 0.39 | 119 / 502 |
| breast | 70% | 21.77 | 323 / 459 | 37% | 0.92 | 415 / 1118 |
| esophagus | 92% | 78.87 | 1328 / 1445 | 15% | 0.31 | 27 / 183 |
| intestine | 87% | 71.56 | 836 / 966 | 17% | 0.33 | 87 / 527 |
| uterus | 82% | 38.99 | 140 / 170 | 9% | 0.69 | 40 / 459 |
| spleen | 89% | 31.70 | 214 / 241 | 0% | 0 | 0 / 0 |
| adipose | 85% | 42.64 | 1019 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 23% | 3.42 | 77 / 328 | 43% | 1.51 | 76 / 178 |
| skin | 59% | 21.64 | 1060 / 1809 | 6% | 0.13 | 27 / 472 |
| thymus | 14% | 4.17 | 91 / 653 | 46% | 9.82 | 277 / 605 |
| kidney | 27% | 8.73 | 24 / 89 | 18% | 0.41 | 164 / 901 |
| blood vessel | 37% | 7.96 | 488 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 36% | 12.39 | 333 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 28% | 2.16 | 8 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 0.39 | 11 / 45 |
| heart | 17% | 2.51 | 145 / 861 | 0% | 0 | 0 / 0 |
| muscle | 13% | 1.75 | 101 / 803 | 0% | 0 | 0 / 0 |
| ovary | 9% | 1.55 | 16 / 180 | 3% | 0.09 | 14 / 430 |
| liver | 8% | 0.96 | 18 / 226 | 2% | 0.06 | 9 / 406 |
| adrenal gland | 1% | 0.11 | 3 / 258 | 2% | 0.04 | 4 / 230 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
| brain | 0% | 0.06 | 12 / 2642 | 0% | 0.01 | 2 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007155 | Biological process | cell adhesion |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0005829 | Cellular component | cytosol |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0030246 | Molecular function | carbohydrate binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0033691 | Molecular function | sialic acid binding |
| Gene name | SIGLEC6 |
| Protein name | Sialic acid-binding Ig-like lectin 6 (Siglec-6) (CD33 antigen-like 1) (CDw327) (Obesity-binding protein 1) (OB-BP1) (CD antigen CD327) |
| Synonyms | OBBP1 CD33L CD33L1 |
| Description | FUNCTION: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
| Accessions | O43699 ENST00000436458.5 [O43699-6] ENST00000391797.3 [O43699-4] ENST00000346477.7 [O43699-3] ENST00000359982.8 [O43699-5] ENST00000343300.8 [O43699-2] ENST00000425629.8 [O43699-1] |
