SGF29 | OmnibusX

Name	Number of supported studies	Average coverage
dendritic cell	3 studies	18% ± 2%	Explore
plasmacytoid dendritic cell	3 studies	19% ± 2%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of SGF29 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	816.01	258 / 258	100%	17.31	230 / 230
esophagus	100%	943.68	1445 / 1445	100%	17.66	183 / 183
liver	100%	603.46	226 / 226	100%	20.31	406 / 406
ovary	100%	1627.60	180 / 180	100%	25.26	430 / 430
thymus	100%	1105.49	653 / 653	100%	31.77	605 / 605
uterus	100%	1634.48	170 / 170	100%	27.70	459 / 459
pancreas	100%	753.09	327 / 328	100%	16.16	178 / 178
kidney	100%	569.08	89 / 89	100%	17.76	897 / 901
skin	100%	697.09	1807 / 1809	100%	18.03	470 / 472
breast	100%	941.62	459 / 459	99%	24.16	1112 / 1118
intestine	100%	1205.97	966 / 966	99%	19.82	524 / 527
prostate	100%	986.23	245 / 245	99%	21.03	499 / 502
stomach	100%	826.75	358 / 359	99%	19.56	284 / 286
bladder	100%	1268.67	21 / 21	99%	24.08	499 / 504
lung	99%	834.04	575 / 578	99%	17.05	1149 / 1155
brain	98%	502.53	2594 / 2642	100%	27.21	705 / 705
adipose	100%	837.58	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	43.00	80 / 80
lymph node	0%	0	0 / 0	100%	34.55	29 / 29
muscle	100%	1394.78	803 / 803	0%	0	0 / 0
spleen	100%	927.78	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	24.92	45 / 45
ureter	0%	0	0 / 0	100%	15.98	1 / 1
blood vessel	100%	994.03	1334 / 1335	0%	0	0 / 0
peripheral blood	99%	760.66	916 / 929	0%	0	0 / 0
heart	98%	470.67	840 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0045995	Biological process	regulation of embryonic development
GO_0034976	Biological process	response to endoplasmic reticulum stress
GO_0071169	Biological process	establishment of protein localization to chromatin
GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0090043	Biological process	regulation of tubulin deacetylation
GO_0006282	Biological process	regulation of DNA repair
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0051302	Biological process	regulation of cell division
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0006355	Biological process	regulation of DNA-templated transcription
GO_0045815	Biological process	transcription initiation-coupled chromatin remodeling
GO_0043484	Biological process	regulation of RNA splicing
GO_0051726	Biological process	regulation of cell cycle
GO_0072686	Cellular component	mitotic spindle
GO_0005654	Cellular component	nucleoplasm
GO_0070461	Cellular component	SAGA-type complex
GO_0140672	Cellular component	ATAC complex
GO_0000124	Cellular component	SAGA complex
GO_0035064	Molecular function	methylated histone binding
GO_0005515	Molecular function	protein binding

Gene name	SGF29
Protein name	SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29) SAGA complex associated factor 29
Synonyms	CCDC101
Description	FUNCTION: Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes . SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3) . In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me . Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival . Also binds non-histone proteins that are methylated on Lys residues: specifically recognizes and binds CGAS monomethylated on 'Lys-506' (By similarity). .
Accessions	ENST00000317058.8 ENST00000564023.1 Q96ES7 H3BN84 ENST00000567564.1 H3BPL5

SGF29 report