I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 5 studies | 25% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 5 studies | 25% ± 4% |
Insufficient scRNA-seq data for expression of SERPINB8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 99% | 1296.01 | 575 / 578 | 98% | 9.40 | 1132 / 1155 |
| esophagus | 95% | 1220.14 | 1366 / 1445 | 99% | 14.11 | 181 / 183 |
| breast | 99% | 822.99 | 454 / 459 | 93% | 6.12 | 1044 / 1118 |
| skin | 100% | 3798.30 | 1809 / 1809 | 91% | 9.66 | 430 / 472 |
| bladder | 95% | 707.81 | 20 / 21 | 95% | 8.19 | 481 / 504 |
| thymus | 95% | 624.29 | 623 / 653 | 93% | 7.48 | 564 / 605 |
| intestine | 87% | 641.97 | 842 / 966 | 98% | 8.72 | 514 / 527 |
| adrenal gland | 99% | 984.99 | 256 / 258 | 85% | 4.73 | 195 / 230 |
| ovary | 83% | 440.18 | 149 / 180 | 92% | 6.16 | 395 / 430 |
| uterus | 72% | 372.82 | 123 / 170 | 92% | 12.44 | 420 / 459 |
| stomach | 66% | 423.56 | 237 / 359 | 97% | 8.31 | 277 / 286 |
| kidney | 66% | 420.96 | 59 / 89 | 82% | 5.24 | 737 / 901 |
| prostate | 81% | 514.10 | 199 / 245 | 67% | 2.48 | 334 / 502 |
| pancreas | 47% | 215.21 | 153 / 328 | 96% | 9.39 | 170 / 178 |
| liver | 69% | 599.77 | 156 / 226 | 72% | 4.52 | 292 / 406 |
| brain | 36% | 171.04 | 961 / 2642 | 90% | 6.47 | 632 / 705 |
| spleen | 100% | 748.22 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.33 | 45 / 45 |
| adipose | 100% | 1229.93 | 1200 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 1414.57 | 1326 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 9.77 | 28 / 29 |
| peripheral blood | 91% | 965.33 | 842 / 929 | 0% | 0 | 0 / 0 |
| heart | 57% | 305.96 | 495 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 26% | 1.01 | 21 / 80 |
| muscle | 19% | 79.35 | 154 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0090136 | Biological process | epithelial cell-cell adhesion |
| GO_0010951 | Biological process | negative regulation of endopeptidase activity |
| GO_0005615 | Cellular component | extracellular space |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004867 | Molecular function | serine-type endopeptidase inhibitor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SERPINB8 |
| Protein name | Serpin family B member 8 Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8) |
| Synonyms | PI8 |
| Description | FUNCTION: Has an important role in epithelial desmosome-mediated cell-cell adhesion. . |
| Accessions | ENST00000397985.7 [P50452-1] A0A1B0GU38 ENST00000636430.1 ENST00000493661.2 A0A087WTX6 P50452 ENST00000542677.5 [P50452-3] ENST00000353706.6 [P50452-1] ENST00000441827.5 H7BXK7 C9JTJ8 ENST00000448851.5 ENST00000397988.7 [P50452-2] C9JVA8 ENST00000295211.5 |
